
What Your Heart Health Means For Fracture Risk
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No, not your risk of a broken heart, but more about its association with bone health and a 93% increased risk of osteoporosis incident fractures:
When your calcium’s in entirely the wrong place
Consider the following:
- You want plenty of calcium in your bones, because that’s one of the (several!) important ingredients for making bones strong.
- You do not want plenty of calcium lining your arteries, because that’s one of the (several!) important ingredients of atherosclerotic plaque.
So, should you get more calcium or less? The crux lies in how your body directs it!
We talk about one of the critical factors in the “learn more” section below (most people don’t know that vitamin K2 is essential for this, and many people have a dietary vitamin K deficiency, because it’s not a vitamin most people think about much.).
Other vitamins are important too, and most people know that vitamin D is a relevant one, but watch out:
- Vitamin D2 vs Vitamin D3: What You Would Benefit From Knowing
- Vit D + Calcium: Too Much Of A Good Thing? ← this also talks about safe and effective doses, and what goes wrong if you take too much
- How Taking Vitamin D Supplements Can Sabotage Your Vitamin D Levels
Hormones are another thing that’s absolutely critical. For women, estrogen (specifically, estradiol) and progesterone are essential for healthy bone turnover. For men, testosterone does the job, but for menopausal women, it usually becomes necessary to supplement with HRT.
For more on that, see:
- The Bare-Bones Truth About Osteoporosis
- Cancer & HRT: What’s Safe? ← for those worried about this; the risks are real for some people with some kinds of HRT, but greatly exaggerated by the press
- The HRT That Prevents Osteoporosis Without Side Effects
So, what does heart health have to do with this?
For a start, there’s a clear relationship between “calcium levels in arteries” and “calcium levels in bones”, and the simplest version is “what gets stuck in the arteries doesn’t make it into the bones”.
So, cardiovascular health becomes critical for bone health.
All so recently (paper published last week, at the time of writing) researchers (Dr. Rafeka Hossain et al.) found that higher cardiovascular risk (measured using the PREVENT risk calculator that we talked about here: What The New Cholesterol Guidelines Mean For You) was linked to higher risks of major osteoporotic and hip fractures in postmenopausal women.
And not a small difference, either: of the 21,300 participants, women in the high CVD risk group had a 93% higher risk of hip fracture compared with low-risk women!
And yes, there was a dose-response effect: fracture risk increased commensurately from borderline to intermediate to high cardiovascular risk.
There are some factors where it’s not that one thing causes the other, but rather they’re both caused by the same thing, e.g. postmenopausal hormonal changes, especially declining estrogen, contribute to both cardiovascular risk and bone loss simultaneously.
There are also some that are more causal in nature, e.g. shared biological pathways passing on chronic inflammation, oxidative stress, impaired calcium regulation, and even reduced blood flow from atherosclerosis itself.
You can read Dr. Hossain’s paper here: The association between 10-year cardiovascular risk and fracture incidence in postmenopausal women: a prospective analysis from the Women’s Health Initiative
Want to learn more?
You might like this book we reviewed a while back:
Vitamin K2 And The Calcium Paradox – by Kate Rhéaume-Bleue ← you may be wondering whether this is somehow 288 pages to say “take vitamin K2”. And, it somewhat is, but there are a lot of details when it comes to things that have historically raised or lowered the amount of vitamin K2 in our diet, what can be done about it in dietary terms if preferring to go all-natural (hint: nattō is an excellent option, but far from the only one), and what other effects vitamin K2 (or its deficiency) can have on us, in many of the body’s systems, far beyond just bone health (and including things as varied as fertility and avoidance of Alzheimer’s).
Take care!
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Over-50s Physio: What My 5 Oldest Patients (Average Age 92) Do Right
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Oftentimes, people of particularly advanced years will be asked their secret to longevity, and sometimes the answers aren’t that helpful because they don’t actually know, and ascribe it to some random thing. Will Harlow, the over-50s specialist physio, talks about the top 5 science-based things that his 5 oldest patients do, that enhances the healthy longevity that they are enjoying:
The Top 5’s Top 5
Here’s what they’re doing right:
Daily physical activity: all five patients maintain a consistent habit of daily exercise, which includes activities like exercise classes, home workouts, playing golf, or taking daily walks. They prioritize movement even when it’s difficult, rarely skipping a day unless something serious happened. A major motivator was the fear of losing mobility, as they had seen spouses, friends, or family members stop exercising and never start again.
Prioritize sleep (but not too much): the patients each average seven hours of sleep per night, aligning with research suggesting that 7–9 hours of sleep is ideal for health. They maintain consistent sleep and wake-up times, which contributes to their well-being. While they allow themselves short naps when needed, they avoid long afternoon naps to avoid disrupting their sleep patterns.
Spend time in nature: spending time outdoors is a priority for all five individuals. Whether through walking, gardening, or simply sitting on a park bench, they make it a habit to connect with nature. This aligns with studies showing that time spent in natural environments, especially near water, significantly reduces stress. When water isn’t accessible, green spaces still provide a beneficial boost to mental health.
Stick to a routine: the patients all value simple daily routines, such as enjoying an evening cup of tea, taking a daily walk, or committing to small gardening tasks. These routines offer mental and physical grounding, providing stability even when life becomes difficult sometimes. They emphasized the importance of keeping routines simple and manageable to ensure they could stick to them regardless of life’s challenges.
Stay curious: a shared trait among the patients was their curiosity and eagerness to learn. They enjoy meeting new people, exploring new experiences, and taking on new challenges. Two of them attended the University of the Third Age to learn new skills, while another started playing bridge as a new hobby. The remaining two have recently made new friends. They all maintain a playful attitude, a good sense of humor, and aren’t afraid to fail or laugh at themselves.
For more on each of these, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
Top 8 Habits Of The Top 1% Healthiest Over-50s ← another approach to the same question, this time with a larger sample size, and/but many younger (than 90s) respondents.
Take care!
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The Doctor’s Kitchen – by Dr. Rupy Aujla
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We’ve featured Dr. Aujla before as an expert-of-the-week, and now it’s time to review a book by him. What’s his deal, and what should you expect?
Dr. Aujla first outlines the case for food as medicine. Not just “eat nutritionally balanced meals”, but literally, “here are the medicinal properties of these plants”. Think of some of the herbs and spices we’ve featured in our Monday Research Reviews, and add in medicinal properties of cancer-fighting cruciferous vegetables, bananas with dopamine and dopamine precursors, berries full of polyphenols, hemp seeds that fight cognitive decline, and so forth.
Most of the book is given over to recipes. They’re plant-centric, but mostly not vegan. They’re consistent with the Mediterranean diet, but mostly Indian. They’re economically mindful (favoring cheap ingredients where reasonable) while giving a nod to where an extra dollar will elevate the meal. They don’t give calorie values etc—this is a feature not a bug, as Dr. Aujla is of the “positive dieting” camp that advocates for us to “count colors, not calories”. Which, we have to admit, makes for very stress-free cooking, too.
Dr. Aujla is himself an Indian Brit, by the way, which gives him two intersecting factors for having a taste for spices. If you don’t share that taste, just go easier on the pepper etc.
As for the medicinal properties we mentioned up top? Four pages of references at the back, for any who are curious to look up the science of them. We at 10almonds do love references!
Bottom line: if you like tasty food and you’re looking for a one-stop, well-rounded, food-as-medicine cookbook, this one is a top-tier choice.
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How To Unfatty A Fatty Liver
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How To Unfatty A Fatty Liver
In Greek mythology, Prometheus suffered the punishment of being chained to a rock, where he would have his liver eaten by an eagle, whereupon each day his liver would grow back, only to be eaten again the next day.
We mere humans who are not Greek gods might not be able to endure quite such punishment to our liver, but it is an incredibly resilient and self-regenerative organ.
In fact, provided at least 51% of the liver is still present and correct, the other 49% will regrow. Similarly, damage done (such as by trying to store too much fat there due to metabolic problems, as in alcoholic or non-alcoholic fatty liver disease) will reverse itself in time, given the chance.
The difference between us and Prometheus
In the myth, Prometheus had his liver regrow overnight every night. But he was a Titan (one of the pre-Olympian gods), and we are not.
In other words: ours don’t recover quite so quickly.
Indeed, the science has good and bad news for us:
❝Liver recolonization models have demonstrated that hepatocytes have an unlimited regenerative capacity. However, in normal liver, cell turnover is very slow.❞
~ Michalopoulos and Bhusan (2020)
Read more: Liver regeneration: biological and pathological mechanisms and implications
If it regenerates, why do people need transplants, and/or die of liver disease?
There are some diseases of the liver that inhibit its regenerative abilities, or (as in the case of cancer) abuse them to our detriment. However, in the case of fatty liver disease, the reason is usually simple:
If the lifestyle factors that caused the liver to become fatty are still there, then its regenerative abilities won’t be able to keep up with the damage that is still being done.
Can we speed it up at all?
Yes! The first and most important thing is to minimize how much ongoing harm you are still doing to it, though.
- If you drink alcohol, stop. According to the WHO, the only amount of alcohol that is safe for you is zero.
- You might like our previous article: How To Reduce Or Quit Alcohol
- Consider your medications, and find out which place a strain on the liver. Many medications are not optional; you’re taking them for an important reason, so don’t quit things without checking with your doctor. Medications that strain the liver include, but are by no means limited to:
- Many painkillers, including acetaminophen/paracetamol (e.g. Tylenol), and ibuprofen
- Some immunosuppressant drugs, including azathioprine
- Some epilepsy drugs, including phenytoin
- Some antibiotics, including amoxicillin
- Statins in general
Note: we are not pharmacists, nor doctors, let alone your doctors.
Check with yours about what is important for you to take, and what alternatives might be safe for you to consider.
Dietary considerations
While there are still things we don’t know about the cause(s) of non-alcoholic fatty liver disease, there is a very strong association with a diet that is:
- high in salt
- high in refined carbohydrates
- e.g. white flour and white flour products such as white bread and white pasta; also the other main refined carbohydrate: sugar
- high in red meat
- high in non-fermented dairy
- high in fried foods.
So, consider minimizing those, and instead getting plenty of fiber, and plenty of lean protein (not from red meat, but poultry and fish are fine iff not fried; beans and legumes are top-tier, though).
Also, hydrate. Most people are dehydrated most of the time, and that’s bad for all parts of the body, and the liver is no exception. It can’t regenerate if it’s running on empty!
Read more: Foods To Include (And Avoid) In A Healthy Liver Diet
How long will it take to heal?
In the case of alcoholic fatty liver disease, it should start healing a few days after stopping drinking. Then, how long it takes to fully recover depends on the extent of the damage; it could be weeks or months. In extreme cases, years, but that is rare. Usually if the damage is that severe, a transplant is needed.
In the case of non-alcoholic fatty liver disease, again it depends on the extent of the damage, but it is usually a quicker recovery than the alcoholic kind—especially if eating a Mediterranean diet.
Read more: How Long Does It Take For Your Liver To Repair Itself?
Take good care of yourself!
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- If you drink alcohol, stop. According to the WHO, the only amount of alcohol that is safe for you is zero.
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How community health screenings get more people of color vaccinated
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U.S. preventive health screening rates dropped drastically at the height of the COVID-19 pandemic. They have yet to go back to pre-pandemic levels, especially for Black and Latine communities.
Screenings, or routine medical checkups, are important ways to avoid and treat disease. They’re key to finding problems early on and can even help save people’s lives.
Community health workers say screenings are also a key to getting more people vaccinated. Screening fairs provide health workers the chance to build rapport and trust with the communities they serve, while giving their clients the chance to ask questions and get personalized recommendations according to their age, gender, and family history.
But systemic barriers to health care can often keep people from marginalized communities from accessing recommended screenings, exacerbating racial health disparities.
Public Good News spoke with Dr. Marie-Jose Francois, president and chief executive officer, and April Johnson, outreach coordinator, at the Center for Multicultural Wellness and Prevention (CMWP), in Central Florida, to learn how they promote the benefits of screening and leverage screenings for vaccination outreach among their diverse communities.
Here’s what they said.
[Editor’s note: This content has been edited for clarity and length.]
PGN: What is CMWP’s mission? How does vaccine outreach fit into the work you do in the communities you serve?
Dr. Marie-Jose Francois: Since 1995, our mission has been to enhance the health, wellness, and quality of life for diverse populations in Central Florida. At the beginning, our main focus was education, wellness, and screening for HIV/AIDS, and we continue to do case management for HIV screening and testing.
When the issue of COVID-19 came into the picture, we included COVID-19 information and education and stressed the importance of screening and receiving vaccinations during all of our outreach activities.
We try to meet the community where they are. Because there is so much misconception—and taboo—in regard to immunization.
April Johnson: So our job is to disperse accurate information. And how we do that is we go into rural communities. We build partnerships with local apartment complexes, hair salons, nail salons, laundromats, and provide a little community engagement, where people just hang out in different areas.
We build gatekeepers in those communities because you first have to get in there. You have to know that they trust you. Being in this field for about 30 years, I’ve [learned that] flexibility is key. Because sometimes you can’t get them from 9 to 5, or [from] Monday through Friday. So, you have to be very flexible in doing the outreach portion in order to get what you need.
I’ve built collaborations with senior citizen centers, community centers, schools, clinics, churches in Orlando and [in] different areas in Orange, Osceola, Seminole, and Lake counties. And we also partner with other community-based organizations to try to make it like a one-stop shop. So, partnership is a big thing.
PGN: How do you promote the importance of preventive screenings in the communities you serve?
M.F.: We try to make them view their health in a more comprehensive way, for them to understand the importance of screening. [That] self care is key, and for them to not be afraid.
We empower them to know what to ask when they go to the doctor. We ask them, ‘Do you know your status? Do you know your numbers?’
For example, if you go to the doctor, do you know your blood pressure? If you’re diabetic? Do you know your hemoglobin (A1C)? Do you know your cholesterol levels?
And now, [we also ask them]: ‘Have you received your flu shot for the year? Have you received all of your vaccine doses for COVID-19?’ We are even adding the mpox vaccine now, based on risk factors.
[We recommend they] ask their provider. For women, [we ask], ‘When do you need to have your mammogram?’ For the men, ‘You need to ask about your PSA and also about when and when to have your colonoscopy based on your age.’
We also try to explain to the community that the more they know their family history, the more they can engage in their own health. Because sometimes you have mom and dad who have a history of cancer. They have a history of diabetes or blood pressure—and they don’t talk to their children. So, we try to [recommend they] talk to their children. Your own family needs to know what’s going on so they can be proactive in their screenings.
PGN: What strategies or methods have you found most effective in getting people screened?
M.F.: Not everybody wants to be screened, not everybody wants to receive vaccines.
But with patience, just give them the facts. It goes right back to education, people have to be assured.
When you talk to them about COVID, or even HIV, you may hear them say, ‘Oh, I don’t see myself at risk for HIV.’ But we have to repeat to them that the more they get screened to make sure they’re OK, the better it is for them. ‘The more you use condoms, [the] safer it is for you.’
In Haitian culture, they listen to the radio. So we use the radio as a tool to educate and deliver information [to] get vaccinated, wash your hands. ‘If you’re coughing, cover your mouth. If you have a fever, wear your masks. Call your doctor.’
In our target population, we have people who have chronic conditions. We have people with HIV. So, we have to motivate them to receive the flu vaccine, to receive the COVID vaccine, to receive that RSV [vaccine], or to get the mpox vaccine. We have people with diabetes, high blood pressure, high cholesterol, depressed immune systems. We have people with lupus, we have people with sickle cell disease.
So, this is a way to [ensure that] whomever you’re talking to one-on-one understands the value of being safe.
This article first appeared on Public Good News and is republished here under a Creative Commons license.
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Vitamin B6 is essential – but too much can be toxic. Here’s what to know to stay safe
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In recent weeks, reports have been circulating about severe reactions in people who’ve taken over-the-counter vitamin B6 supplements.
Vitamin B6 poisoning can injure nerves and lead to symptoms including numbness, tingling and even trouble walking and moving.
In some cases, those affected didn’t know the product contained any vitamin B6.
So what is vitamin B6, where is it found and how much is too much? Here’s what you need to know about this essential nutrient.
Kim Kuperkova/Shutterstock What is vitamin B6?
Vitamin B6 (also known as pyridoxine) is a group of six compounds that share a similar chemical structure.
It is an essential nutrient, meaning we need it for normal body functions, but we can’t produce it ourselves.
Adults aged 19–50 need 1.3mg of vitamin B6 per day. The recommended dose is lower for teens and children, and higher for those aged 51 and over (1.7mg for men and 1.5mg for women) and people who are breastfeeding or pregnant (1.9mg).
Most of us get this in our diet – largely from animal products, including meat, dairy and eggs.
The vitamin is also available in a range of different plant foods, including spinach, kale, bananas and potatoes, so deficiency is rare, even for vegetarians and vegans.
The vitamin B6 we consume in the diet is inactive, meaning the body can’t use it. To activate B6, the liver transforms it into a compound called pyridoxal-5’-phosphate (PLP).
In this form, vitamin B6 helps the body with more than 140 cellular functions, including building and breaking down proteins, producing red blood cells, regulating blood sugar and supporting brain function.
Vitamin B6 is important for overall health and has also been associated with reduced cancer risk and inflammation.
Despite being readily available in the diet, vitamin B6 is also widely included in various supplements, multivitamins and other products, such as Berocca and energy drinks.
Most people get enough vitamin B6 from their diet. Tatjana Baibakova/Shutterstock Should we be worried about toxicity?
Vitamin B6 toxicity is extremely rare. It almost never occurs from dietary intake alone, unless there is a genetic disorders or disease that stops nutrient absorption (such as coeliac disease).
This is because all eight vitamins in the B group are water-soluble. If you consume more of the vitamin than your body needs, it can be excreted readily and harmlessly in your urine.
However, in some rare cases, excessive vitamin B6 accumulates in the blood, resulting in a condition called peripheral neuropathy. We’re still not sure why this occurs in some people but not others.
Peripheral neuropathy occurs when the sensory nerves – those outside our brain and spinal cord that send information to the central nervous system – are damaged and unable to function. This can be caused by a wide range of diseases (and is most well known in type 2 diabetes).
The most common symptoms are numbness and tingling, though in some cases patients may experience difficulty with balance or walking.
We don’t know exactly how excess vitamin B6 causes peripheral neuropathy, but it is thought to interfere with how the neurotransmitter GABA sends signals to the sensory nerves.
Vitamin B6 can cause permanent damage to nerves. Studies have shown symptoms improved when the person stopped taking the supplement, although they didn’t completely resolve.
What is considered excessive? And has this changed?
Toxicity usually occurs only when people take supplements with high doses of B6.
Until 2022, only products with more than 50mg of vitamin B6 were required to display a warning about peripheral neuropathy. But the Therapeutic Goods Administration lowered this and now requires any product containing more than 10mg of vitamin B6 to carry a warning.
The Therapeutic Goods Administration has also halved the daily upper limit of vitamin B6 a product can provide – from 200mg to 100mg.
These changes followed a review by the administration, after receiving 32 reports of peripheral neuropathy in people taking supplements. Two thirds of these people were taking less than 50mg of vitamin B6.
The Therapeutic Goods Administration acknowledges the risk varies between individuals and a lot is unknown. Its review could not identify a minimum dose, duration of use or patient risk factors.
But I thought B vitamins were good for me?
Too much of anything can cause problems.
The updated guidelines are likely to significantly lower the risk of toxicity. They also make consumers more aware of which products contain B6, and the risks.
The Therapeutic Goods Administration will continue to monitor evidence and revise guidelines if necessary.
While vitamin B6 toxicity remains very rare, there are still many questions about why some people get peripheral neuropathy with lower dose supplements.
It could be that some specific vitamin B compounds have a stronger effect, or some people may have genetic vulnerabilities or diseases which put them at higher risk.
So what should I do?
Most people don’t need to actively seek vitamin B6 in supplements.
However, many reports to the Therapeutic Goods Administration were of vitamin B6 being added to supplements labelled as magnesium or zinc – and some weren’t aware they were consuming it.
It is important to always check the label if you are taking a new medicine or supplement, especially if it hasn’t been explicitly prescribed by a health-care professional.
Be particularly cautious if you are taking multiple supplements. While one multivitamin is unlikely to cause an issue, adding a magnesium supplement for cramping, or a zinc supplement for cold and flu symptoms, may cause an excessive vitamin B6 dose over time, and increase your risk.
Importantly, pay attention to symptoms that may indicate peripheral neuropathy, such as pins and needles, numbness, or pain in the feet or hands, if you do change or add a supplement.
Most importantly, if you need advice, you should talk to your doctor, dietitian or pharmacist.
Vasso Apostolopoulos, Distinguished Professor, Professor of Immunology, RMIT University and Jack Feehan, Vice Chancellors Senior Research Fellow in Immunology, RMIT University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Bell Pepper vs Celery – Which is Healthier?
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Our Verdict
When comparing bell peppers to celery, we picked the celery.
Why?
First, you might remember that different color bell peppers have different nutritional profiles. So, you might be wondering why we didn’t specify the color.
The reason is: the things that differ from one color to another are important differences between the respective bell peppers, but they make no difference to this comparison, as for any given nutrient that changes from one color to another, it doesn’t change the outcome, because the numbers are still on the same side relative to celery.
With that in mind…
It was close!
In terms of macros, there’s really nothing between them, so the first round’s a tie.
In the category of vitamins, bell peppers have more of vitamins B1, B3, B6, C, and E, while celery has more of vitamins A, B2, B5, B7, B9, and K, yielding a marginal victory to celery here.
Looking at minerals, bell peppers have more coper, iron, and manganese, while celery has more calcium, magnesium, phosphorus, potassium, and selenium, winning another round.
In other considerations, bell peppers have more carotenoids such as lutein, while celery is rather higher in polyphenols, so we’ll call this round a tie.
Adding up the sections makes for a modest-yet-clear overall win for celery, but by all means enjoy either or both, as diversity is best!
Want to learn more?
You might like:
- Which Bell Peppers To Pick? A Spectrum Of Specialties ← for the differences between the different colors
- 21 Most Beneficial Polyphenols & What Foods Have Them
Enjoy!
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