The Four Pillar Plan – by Dr. Rangan Chatterjee
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Dr. Rangan Chatterjee, a medical doctor, felt frustrated with how many doctors in his field focus on treating the symptoms of disease, rather than the cause. Sometimes, of course, treating the symptom is necessary too! But neglecting the cause is a recipe for long-term woes.
What he does differently is take lifestyle as a foundation, and even that, he does differently than many authors on the topic. How so, you may wonder?
Rather than look first at exercise and diet, he starts with “relax”. His rationale is reasonable: diving straight in with marathon training or a whole new diet plan can be unsustainable without this as a foundation to fall back on.
Many sources look first at exercise (because it can be a very simple “prescription”) before diet (often more complex)… but how does one exercise well with the wrong fuel in the tank? So Dr. Chatterjee’s titular “Four Pillars” come in the following order:
- Relax
- Eat
- Move
- Sleep
He also goes for “move” rather than “exercise” as the focus here is more on minimizing time spent sitting, and thus involving a lot of much more frequent gentle activities… rather than intensive training programs and the like.
And as for sleep? Yes, that comes last because—no matter how important it is—the other things are easier to directly control. After all, one can improve conditions for sleep, but one cannot simply choose to sleep better! So with the other three things covered first, good sleep is the fourth and final thing to fall into place.
All in all, this is a great book to cut through the catch-22 problem of lifestyle factors negatively impacting each other.
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The Minerals That Neutralize Viruses (While Being Harmless To Humans)
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Researchers in Estonia and Sweden (it was a joint project, with five researchers from each country) have found a way to use titanium dioxide nanoparticles to neutralize viruses, including COVID & flu.
Titanium dioxide, yes, the common additive to foods, cosmetics, and more (in most cases, added as a non-bleaching whitening agent—simply, titanium dioxide is body-safe, white in color, and very reflective, making it a brilliant, shiny white). Also used in sunscreens, for its excellent safety profile and again, its full-spectrum reflectiveness.
See also: Who Screens The Sunscreens?
How it works
Some viruses, including coronaviruses and influenza viruses, have an outer layer that’s a lipid membrane. The researchers found (by testing against multiple viruses, and by using a control of silicotungstate polyoxymethalate nanoparticles), that the ability of titanium dioxide to bind to phospholipids (and ability that the silicotungstate polyoxymethalate doesn’t have) means that the nanoparticles bind to the virus’s outer case, thus preventing it from effectively entering human cells (which it needs to do in order to infect the host, as this is how viruses replicate themselves).
What this means, in practical terms
While more research will be needed to know whether this can be used in the medicinal sense, it already means that a nanoparticle spray can be used to create virus-neutralizing layers on surfaces and in air filters. This alone could greatly reduce transmission in enclosed spaces such as public transport (ranging from taxis to airplanes), as well as other places where people get packed into a small space.
If you have an air purifier at home, keep an eye out for when improved filters arrive on the market!
See also: What’s Lurking In Your Household Air?
Wait, you said “minerals”; are there more?
It seems so, but we can’t truly say for sure until they’ve been tested. However, the researchers see no reason why other small metal oxides that bind strongly to phospholipids shouldn’t work exactly the same way—which would include iron oxide (yes, as in rust) and aluminum oxide (the coating that automatically forms immediately when aluminum is exposed to oxygen (aluminum is so reactive to oxygen, that it’s almost impossible to get aluminum without an oxidized surface, unless you use something else to coat it, or cut it in an oxygen-free atmosphere and keep it there).
You can read the paper itself here:
Molecular mechanisms behind the anti corona virus activity of small metal oxide nanoparticles
And on a related note (different scientists, different science, similar principle, though, using mineral nanotechnology to kill microbes):
❝Researchers report that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, anti-inflammatory and biocompatible properties. They say these results show these tannic acid and copper(II) phosphate sprouted nanoflower bandages are promising candidates for treating infections and inflammatory conditions.❞
Read in full: This delicate nanoflower is downright deadly to bacteria
Want to learn more?
Check out:
Move over, COVID and Flu! We Have “Hybrid Viruses” To Contend With Now
Take care!
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How To Reduce Cortisol Levels Naturally
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Cortisol is a hormone that is important for us (we’d struggle to get up in the morning without it, for a start), but in this modern world we often have too much of it, too much of the time. How can we rebalance it? Dr. Mindy Pelz explains:
Lifestyle adjustments
A note in advance: the video makes frequent reference to things that “spike cortisol levels”, but this is probably intended as a stand-in for “raise cortisol levels”. Because, unlike for some things, in the case of cortisol, spikes aren’t usually a problem (indeed, they can be beneficial, and this is a large part of why cold showers and ice baths can be healthy; it’s an artificially induced cortisol spike, and this hormesis has an assortment of healthy benefits, each related to improving our body’s ability to switch quickly between states as appropriate); rather, it’s chronically high cortisol levels that are the problem. However, the video discusses things that can increase resting cortisol levels, so where she says “spike”, we suggest to read “raise”.
Dr. Pelz, an advocate of intermittent fasting, mentions that done incorrectly and/or for the same way for too long, fasting can raise cortisol levels and thus sabotage our efforts—so varying our fasting style can help avoid that. For example, 16:8, 5:2, longer fasts less frequently, etc.
On the topic of food, she also warns us of the dangers of ultra-processed food, harmful oils, and foods with added sugar, as these can all raise cortisol levels.
When it comes to exercise, she notes that intense exercise without adequate recovery can raise cortisol levels, so again it’s good to mix up one’s methods, vary one’s exercise routine, and allow each well-worked muscle-group adequate rest afterwards.
Dr. Pelz also talks mindset, and has her own interesting way of framing the well-established science that chronic stress means chronically high stress hormone (cortisol) levels; Dr. Pelz prefers to see it as negative vs positive thoughts, environments, etc.
Any discussion of cortisol management would be incomplete without discussing the importance of good quality sleep. Dr. Pelz doesn’t mention this at all in her video, but it’s important to bear in mind too!
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Want to learn more?
You might also like to read:
Lower Your Cortisol! (Here’s Why & How)
Take care!
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Chromium Picolinate For Blood Sugar Control & Weight Loss
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First, a quick disambiguation:
- chromium found in food, trivalent chromium of various kinds, is safe (in the quantities usually consumed) and is sometimes considered an essential mineral, sometimes considered unnecessary but beneficial. It’s hard to know for sure, since it’s in a lot of foods (naturally, like many trace elements)
- chromium found in pollution, hexavalent chromium (so: twice as many cationic bonds, if this writer’s chemistry serves her correctly) is poisonous.
We’re going to be writing about the food kind, which is also possible to take as a supplement.
In this case, supplementing vs getting from food is quite a big difference, by the way, since (unlike for a lot of things, which are often the other way around) the bioavailability of chromium from food is very low (around 2.5%), whereas chromium picolinate, one of the most commonly-used supplement forms, boasts higher bioavailability.
Does it work for blood sugars?
Yes, it does! At least, it does in the case of people with type 2 diabetes. Rather than bombard you with many individual studies, here’s a systematic review and meta-analysis of 22 criteria-meeting randomized clinical trials that found:
❝The available evidence suggests favourable effects of chromium supplementation on glycaemic control in patients with diabetes.
Chromium monosupplement may additionally improve triglycerides and HDL-C levels.❞
Type 1 diabetes does not have anything like the same weight of evidence, and indeed,
we couldn’t find a single human study. It was beneficial for mice with artificially-induced T1D, thoughwait no, we have an update! We found literally a single human study:Chromium picolinate supplementation for diabetes mellitus
Literally, as in: it’s a case study of one person, and the results were a modest reduction in Hb A1c levels after 3 months of 600μg daily; the researchers concluded that ❝chromium picolinate continues to fall squarely within the scope of “alternative medicine,” with both unproven benefits and unknown risks❞.
As for people without diabetes, it may reduce the risk of diabetes:
Risk of Type 2 Diabetes Is Lower in US Adults Taking Chromium-Containing Supplements
However! This was an observational study, and correlation ≠ causation.
Furthermore, they said:
❝Over one-half the adult US population consumes nutritional supplements, and over one-quarter consumes supplemental chromium. The odds of having T2D were lower in those who, in the previous 30 d, had consumed supplements containing chromium❞
That “over one-quarter consumes supplemental chromium” brought our attention to the fact that this is not talking about specifically chromium “monosupplements” (definitely not quarter of the adult population take those), but rather, “multivitamin and mineral” supplements that also contain a tiny amount (often under 50μg) of chromium.
In other words, this ruins the data and honestly the benefit could have been from anything in the “multivitamin and mineral” supplement, or indeed, could just be “the kind of person who takes supplements is the kind of person who lives a lifestyle that is less conducive to becoming diabetic”.
Does it work for weight loss?
We’re running out of space here, so we’ll be brief:
No.
There are many papers that have concluded this, but here are two:
Chromium picolinate supplementation for overweight or obese adults
and
Is it safe?
Science’s current best answer is “we don’t know; it hasn’t been tested enough; we haven’t even established the tolerable upper limit, which is usually step 1 of establishing safety”.
Nor is there an estimated average requirement (if indeed there even is a requirement, which question is also not as yet answered conclusively by science), and science falls back to “here’s an average of what people consume in their diet, so that’s probably safe, we guess”.
(that average was reckoned as 25μg/day for young women and 25μg/day for young men, by the way; older ages not as yet reckoned)
You can read about this sorry state of affairs here.
Want to try some?
Notwithstanding the above lack of data for safety, it does have benefits for blood sugars, so if that’s a gamble you’re willing to make, then here’s an example product on Amazon.
Note: the dosage per capsule there (800μg) is half of the low end of the dose that was implicated in the serious kidney condition caused in this case study (1200–2400μg), so if you are going to try it, we strongly recommend not taking more than one per day.
Take care!
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Fiber Fueled – by Dr. Will Bulsiewicz
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We generally know that for gut health we should eat fiber, but what of the balances of different sorts of fiber?
That’s one of the main things that make this book stand out—fostering diversity in our microbiome by fostering diversity in our diet. Specifically, diversity of fiber-containing foods.
The book is part “science made easy for the lay reader”, and part recipe book. The recipes come with shopping lists and a meal planner, though we would recommend to use those as a guide rather than to try to adhere perfectly to them.
In particular, this reviewer would encourage much more generous use of healthful seasonings… and less reliance on there being leftovers several days later (tasty food gets gone quickly in this house!)
As for the science, the feel of this is more like reading a science-based observational documentary with explanations, than of reading a science textbook. Studies are mentioned in passing, but not dissected in any detail, and the focus is more on getting the key learnings across.
Bottom line: if you’d like to boost not just the amount, but also the diversity, of fiber in your diet, and reap the gut-health rewards, this book is a great guide for that!
Click here to get your copy of “Fiber Fueled” from Amazon today!
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An Apple (Cider Vinegar) A Day…
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An Apple (Cider Vinegar) A Day…
You’ve probably heard of people drinking apple cider vinegar for its health benefits. It’s not very intuitive, so today we’re going to see what the science has to say…
Apple cider vinegar for managing blood sugars
Whether diabetic, prediabetic, or not at all, blood sugar spikes aren’t good for us, so anything that evens that out is worth checking out. As for apple cider vinegar…
Diabetes Control: Is Vinegar a Promising Candidate to Help Achieve Targets?
…the answer found by this study was “yes”, but their study was small, and they concluded that more research would be worthwhile. So…
…was also a small study, with the same (positive) results.
But! We then found a much larger systematic review was conducted, examining 744 previously-published papers, adding in another 14 they found via those. After removing 47 duplicates, and removing another 15 for not having a clinical trial or not having an adequate control, they concluded:
❝In this systematic review and meta-analyses, the effect of vinegar consumption on postprandial glucose and insulin responses were evaluated through pooled analysis of glucose and insulin AUC in clinical trials. Vinegar consumption was associated with a statistically significant reduction in postprandial glucose and insulin responses in both healthy participants and participants with glucose disorder.❞
~ Sishehbor, Mansoori, & Shirani
Check it out:
Apple cider vinegar for weight loss?
Yep! It appears to be an appetite suppressant, probably moderating ghrelin and leptin levels.
But…
As a bonus, it also lowers triglycerides and total cholesterol, while raising HDL (good cholesterol), and that’s in addition to doubling the weight loss compared to control:
How much to take?
Most of these studies were done with 1–2 tbsp of apple cider vinegar in a glass of water, at mealtime.
Obviously, if you want to enjoy the appetite-suppressant effects, take it before the meal! If you forget and/or choose to take it after though, it’ll still help keep your blood sugars even and still give you the cholesterol-moderating benefits.
Where to get it?
Your local supermarket will surely have it. Or if you buy it online, you can even get it in capsule form!
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Dandelion: Time For Evidence On Its Benefits?
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In recent decades often considered a weed, now enjoying a resurgence in popularity due its benefits for pollinators, this plant has longer-ago been enjoyed as salad (leaves) or as a drink (roots), and is typically considered to have diuretic and digestion-improving properties. So… Does it?
Diuretic
Probably! Because of the ubiquity of anecdotal evidence, this hasn’t been well-studied, but here’s a small (n=17) study that found that it significantly increased urination:
The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day
You may be thinking, “you usually do better than an n=17 study” and yes we do, but there’s an amazing paucity of human research when it comes to dandelions, as you’ll see:
Digestion-improving
There’s a lot of fiber in dandelion greens and roots both, and eating unprocessed or minimally-processed plants is (with obvious exceptions, such as plants that are poisonous) invariably going to improve digestion just by virtue of the fiber content alone.
As for dandelions, the roots are rich in inulin, a great prebiotic fiber that indeed definitely helps:
Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review)
When it comes to studies that are specifically about dandelions, however, we are down to animal studies, such as:
The effect of Taraxacum officinale on gastric emptying and smooth muscle motility in rodents
Note that this is not about the fiber; this is about the plant extract (so, no fiber), and how it gets the intestinal muscles to do their thing with more enthusiasm. Of course you, dear reader, are probably not a rodent, we can’t say for sure that this will have this effect in humans. However, generally speaking, what works for mammals works for mammals, so it probably indeed helps.
For liver health
More about rats and not humans, but again, it’s promising. Dandelion extract appears to protect the liver, reducing the damage in the event of induced liver failure:
In other words: the researchers poisoned the rats, and those who took dandelion extract suffered less liver damage than those who didn’t.
…and more?
It may help improve blood triglycerides and reduce ischemic stroke risk, but most of this research is still in non-human animals:
And while we’re on the topic of blood, it likely has blood-sugar-lowering effects too; once again (you guessed it), mostly non-human animal studies, though, with some in vitro studies:
The Physiological Effects of Dandelion (Taraxacum Officinale) in Type 2 Diabetes
Want to try some?
We don’t sell it, but if you have a garden, that’s a great place to grow this very easy-to-grow plant without having to worry about pesticides etc.
Alternatively, if you’d like to buy it in supplement form, here’s an example product on Amazon 😎
Enjoy!
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