How Does Alcohol Cause Blackouts?

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Sometimes people who have never experienced an alcoholic blackout wonder “is it real, or is it just a convenient excuse to avoid responsibility/embarrassment with regard to things done while drunk?”

In 1969 (so, still in the era of incredibly unethical psychological experiments that ranged from the 50s into the 70s), Dr. Donald Goodwin conducted a study in which intoxicated participants were asked to recall an object they had just seen. Most succeeded initially, but half were unable to remember the object just 30 minutes later, demonstrating alcohol-induced memory blackouts.

But, is it any different from regular forgetting? And the answer is: yes, it is indeed different.

The memories that never got stored

Ethanol, the active compound in alcohol, is lipophilic, enabling it to cross the blood-brain barrier and disrupt brain function. It impairs all kinds of things, including decision-making, impulse control, motor skills, and, notably, memory networks—which is what we’re looking at today.

Memory formation (beyond “working memory”, which is the kind that enables you to have an idea of what you were just doing, and carry out simple plans like “pick up this cup, raise it to my mouth, and take a sip”, without forgetting partway through) relies on a process called long-term potentiation (LTP), which strengthens neural connections to store information. Ethanol disrupts this process, preventing memory storage and causing blackouts.

In effect, this means you didn’t just forget a memory; you never stored it in the first place. For this reason, experiences from during an alcoholic blackout cannot be retrieved in the same ways we might retrieve other memories (e.g. in regular forgetting, it’s possible that a context clue jogs our memory and then we remember the experience—because in regular forgetting, the memory was in there; we just didn’t recall it until we were reminded).

Blackouts (in which the memory is never stored in the first place) typically occur when blood alcohol concentration (BAC) exceeds 0.16, while lower levels can result in partial memory loss (brownouts) in which some things may be recalled, but not others. Factors such as dehydration, genetics, medications, food consumption, and age influence the likelihood of complete blackouts.

While alcohol’s residual effects typically subside within a day, repeated over-drinking can cause permanent neuron damage, as well as of course plenty of damage to other organs in the body (especially the liver and gut).

For more on all of this, enjoy:

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Want to learn more?

You might also like to read:

What Happens To Your Body When You Stop Drinking Alcohol

Take care!

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  • The Bare-Bones Truth About Osteoporosis

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    In yesterday’s issue of 10almonds, we asked you “at what age do you think it’s important to start worrying about osteoporosis?”, and here’s the spread of answers you gave us:

    The Bare-bones Truth About Osteoporosis

    In yesterday’s issue of 10almonds, we asked you “at what age do you think it’s important to start worrying about osteoporosis?”, and here’s the spread of answers you gave us:

    At first glance it may seem shocking that a majority of respondents to a poll in a health-focused newsletter think it’ll never be an issue worth worrying about, but in fact this is partly a statistical quirk, because the vote of the strongest “early prevention” crowd was divided between “as a child” and “as a young adult”.

    This poll also gave you the option to add a comment with your vote. Many subscribers chose to do so, explaining your choices… But, interestingly, not one single person who voted for “never” had any additional thoughts to add.

    We loved reading your replies, by the way, and wish we had room to include them here, because they were very interesting and thought-provoking.

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    The body is constantly repairing itself. Its ability to do that declines with age. Until about 35 on average, we can replace bone mineral as quickly as it is lost. After that, we lose it by up to 1% per year, and that rate climbs after 50, and climbs even more steeply for those who go through (untreated) menopause.

    Losing 1% per year might not seem like a lot, but if you want to live to 100, there are some unfortunate implications!

    About that menopause, by the way… Because declining estrogen levels late in life contribute significantly to osteoporosis, hormone replacement therapy (HRT) may be of value to many for the sake of bone health, never mind the more obvious and commonly-sought benefits.

    Learn more: Management of osteoporosis in postmenopausal women: the 2021 position statement of The North American Menopause Society

    On the topic of that glass of milk…

    • Milk is a great source of calcium, which is useless to the body if you don’t also have good levels of vitamin D and magnesium.
    • People’s vitamin D levels tend to directly correlate to the level of sun where they live, if supplementation isn’t undertaken.
    • Plant-based milks are usually fortified with vitamin D (and calcium), by the way.
    • Most people are deficient in magnesium, because green leafy things don’t form as big a part of most people’s diets as they should.

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    Next most common myth: “bone health is all about calcium”

    We spoke a little above about the importance of vitamin D and magnesium for being able to properly use that. But potassium is also critical:

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    While we’re on the topic…

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    You might want to check out this well-sourced LiveStrong article:

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  • Sesame & Peanut Tofu

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    Yesterday we learned how to elevate tofu from “nutrition” to “nutritious tasty snack” with our Basic Baked Tofu recipe; today we’re expanding on that, to take it from “nutritious tasty snack” to “very respectable meal”.

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    For those of us for whom mobility and pain-free movement are top priorities, this book has us covered. So what’s different here, compared to your average stretching book?

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  • Mythbusting Moldy Food

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Most Food Should Not Be Fuzzy

    In yesterday’s newsletter, we asked you for your policy when it comes to mold on food (aside from intentional mold, e.g. blue cheese etc), and the responses were interesting:

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    True! We don’t think this is contentious so we’ll not spend much time on it, but just for the sake of being methodical: foods that are supposed to have mold on, including many kinds of cheese and even some kinds of cured meat (salami is an example; that powdery coating is mold).

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    The USDA has a handy downloadable factsheet:

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    False, generally. There are of course countless types of mold, but not only are many of them pathogenic (mycotoxins), but also, a food that has mold will usually also have pathogenic bacteria along with the mold.

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    Stay safe!

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  • Pulse – by Jenny Chandler

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Beans, chickpeas, and lentils are well-established super-healthy foods, but they’re often not a lot of people’s favorite. And why? Usually because of unhappy associations with boring dishes that can barely be called dishes.

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    Click here to check out Pulse, and expand your kitchen repertoire!

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