Comfortable with Uncertainty – by Pema Chödrön

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This book is exactly what the subtitle claims it to be: 108 teachings on cultivating fearlessness and compassion. They are short extracts, entire of themselves, taken from Chödrön’s wider work and arranged to offer her insights and advices on this one topic, in one place.

It is worth noting, by the way, that the author is a Buddhist nun, and as such, the principles and practices are Buddhist in origin. If that’s a problem for you, then this book will not be for you. It does not, however, require that the reader be Buddhist to benefit, simply that one has a will to be calm in the face of chaos, and yet not indifferent—rather, to take on the challenges of life with a whole heart.

And about that compassion? This is about alleviating suffering; your own, and the suffering in the world as a whole, increasingly uncertain as this world is. And being brave enough to do that, in a world that is not always gentle.

The style is idiosyncratic, and you will likely love it or hate it. If you love it, then you will find this book at once both soothing and empowering; if not, you will put the book down and pick up a book on CBT or something instead.

Bottom line: this book absolutely does deliver on its title/subtitle promises—provided you, dear reader, internalize it and practise it.

Click here to check out Comfortable with Uncertainty, and get comfortable with uncertainty!

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  • Signs Of Low Estrogen In Women: What Your Skin, Hair, & Nails Are Trying To Tell You

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    Skin, hair, and nails are often thought of purely as a beauty thing, but in fact they can be indicative of a lot of other aspects of health. Dr. Andrea Suarez takes us through some of them in this video about the systemic (i.e., whole-body, not just related to sex things) effects of estrogen, and/or a deficiency thereof.

    Beyond the cosmetic

    Low estrogen levels are usual in women during and after untreated menopause, resulting in various changes in the skin, hair, and nails, that reflect deeper issues, down to bone health, heart health, brain health, and more. Since we can’t see our bones or hearts or brains without scans (or a serious accident/incident), we’re going to focus on the outward signs of estrogen deficiency.

    Estrogen helps maintain healthy collagen production, skin elasticity, wound healing, and moisture retention, making it essential for youthful and resilient skin. Declining estrogen levels with menopause lead to a thinner epidermis, decreased collagen production, and more pronounced wrinkles. Skin elasticity also diminishes, which slows the skin’s ability to recover from stretching or deformation. Wound healing also becomes slower, increasing the risk of infections and extended recovery periods after injuries or surgeries—bearing in mind that collagen is needed in everything from our skin to our internal connective tissue (fascia) and joints and bones. So all those things are going to struggle to recover from injury (and surgery is also an injury) without it.

    Other visible changes associated with declining estrogen include significant dryness as a result of reduced hyaluronic acid and glycosaminoglycan production, which are essential for moisture retention. The skin becomes more prone to irritation and increased water loss. Additionally, estrogen deficiency results in less resistance to oxidative stress, making the skin more susceptible to damage from environmental factors such as UV radiation and pollution, as well as any from-the-inside pollution that some may have depending on diet and lifestyle.

    Acne and enlarged pores are associated with increased testosterone, but testosterone and estrogen are antagonistic in most ways, and in this case a decrease in estrogen will do the same, due increased unopposed androgen signaling affecting the oil glands. The loss of supportive collagen also causes the skin around pores to lose structure, making them appear larger. The reduction in skin hydration further exacerbates the visibility of pores and can contribute to the development of blackheads due to abnormal cell turnover.

    Blood vessel issues tend to arise as estrogen levels drop, leading to a reduction in angiogenesis, i.e. the formation and integrity of blood vessels. This results in more fragile and leaky blood vessels, making the skin more prone to bruising, especially on areas frequently exposed to the sun, such as the backs of the hands. This weakened vasculature also further contributes to the slower wound healing that we talked about, due to less efficient delivery of growth factors.

    Hair and nail changes often accompany estrogen deficiency. Women may notice hair thinning, increased breakage, and a greater likelihood of androgenic alopecia. The texture of the hair can change, becoming more brittle. Similarly, nails can develop ridges, split more easily, and become more fragile due to reduced collagen and keratin production, which also affects the skin around the nails.

    As for what to do about it? Management options for estrogen-deficient skin include:

    • Bioidentical hormone replacement therapy (HRT), which can improve skin elasticity, boost collagen production, and reduce dryness and fragility, as well as addressing the many more serious internal things that are caused by the same deficiency as these outward signs.
    • Low-dose topical estrogen cream, which can help alleviate skin dryness and increase skin strength, won’t give the systemic benefits (incl. to bones, heart, brain, etc) that only systemic HRT can yield.
    • Plant-based phytoestrogens, which are not well-evidenced, but may be better than nothing if nothing is your only other option. However, if you are taking anything other form of estrogen, don’t use phytoestrogens as well, or they will compete for estrogen receptors, and do the job not nearly so well while impeding the bioidentical estrogen from doing its much better job.

    And for all at any age, sunscreen continues to be one of the best things to put on one’s skin for general skin health, and this is even more true if running low on estrogen.

    For more on all of this, enjoy:

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    Want to learn more?

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    These Signs Often Mean These Nutrient Deficiencies (Do You Have Any?)

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  • 10 Skin Warning Signs You Should Never Ignore

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    Do you have armpits? Don’t ignore them!

    Heed the signs:

    Without further ado, they are:

    1. Acanthosis nigricans: dark, velvety brown skin thickening on the neck, underarms, backs of the hands, or sides of the face can signal insulin resistance, prediabetes, or PMOS. The good news, however, is that despite common concerns of such, sudden widespread onset is rarely associated with cancer.
    2. Unexplained bruising: bruises appearing without remembered injury may be linked to platelet disorders, clotting disorders, vitamin deficiencies, liver disease, certain cancers, or medications such as blood thinners and corticosteroids; bruising accompanied by nosebleeds, bleeding gums, or large purple patches is especially concerning and merits medical attention.
    3. Yellowing of the skin or eyes: jaundice can indicate liver disease, bile duct obstruction, or increased breakdown of red blood cells; yellowing often appears under the tongue and inside the mouth before becoming obvious elsewhere. It’s worth knowing that unlike harmless carotene-related skin discoloration (i.e. you drank a lot of carrot juice and turned orange), jaundice also affects the eyes and mouth.
    4. Severe itching without a rash: persistent whole-body itching lasting more than six weeks with no visible rash can be associated with liver disease, kidney disease, thyroid disorders, iron deficiency, or cancers such as Hodgkin lymphoma. Itching triggered by showering is another warning sign.
    5. Thick, waxy, or tight skin: swollen, shiny, waxy skin on the shins may occur with Graves’ disease, while skin tightening on the fingers may suggest diabetes or Scleroderma, particularly when hand mobility becomes restricted.
    6. Butterfly rash on the face: a rash across the cheeks and nose that spares the folds beside the nose famously may indicate systemic lupus erythematosus, especially if it worsens with sun exposure and is accompanied by fatigue or joint pain.
    7. Dark streaks under the nails: a new dark band in a single nail, particularly one that widens, contains multiple colors, or extends onto the surrounding skin, can be a warning sign of melanoma and should be evaluated for such.
    8. Sudden hair shedding: rapid diffuse hair loss, known as telogen effluvium, often occurs about three months after a physical stressor and may be associated with thyroid disease, iron deficiency, infection, surgery, trauma, nutritional deficiencies, pregnancy, or rapid weight loss.
    9. Non-healing wounds or recurrent infections: cuts, scrapes, or ulcers that remain open for more than four weeks generally suggest poor circulation, vascular disease, diabetes, or impaired immune function.
    10. Yellow, thick, or crumbly nails: commonly caused by a fungal infection, but when accompanied by respiratory symptoms and leg swelling, they may indicate bigger problems and should be checked out.

    For more on all of this plus visual illustrations, enjoy:

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    Want to learn more?

    You might also like:

    What Your Skin Texture Says About Your Health

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  • If I’m diagnosed with one cancer, am I likely to get another?

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    Receiving a cancer diagnosis is life-changing and can cause a range of concerns about ongoing health.

    Fear of cancer returning is one of the top health concerns. And managing this fear is an important part of cancer treatment.

    But how likely is it to get cancer for a second time?

    Why can cancer return?

    While initial cancer treatment may seem successful, sometimes a few cancer cells remain dormant. Over time, these cancer cells can grow again and may start to cause symptoms.

    This is known as cancer recurrence: when a cancer returns after a period of remission. This period could be days, months or even years. The new cancer is the same type as the original cancer, but can sometimes grow in a new location through a process called metastasis.

    Actor Hugh Jackman has gone public about his multiple diagnoses of basal cell carcinoma (a type of skin cancer) over the past decade.

    The exact reason why cancer returns differs depending on the cancer type and the treatment received. Research is ongoing to identify genes associated with cancers returning. This may eventually allow doctors to tailor treatments for high-risk people.

    What are the chances of cancer returning?

    The risk of cancer returning differs between cancers, and between sub-types of the same cancer.

    New screening and treatment options have seen reductions in recurrence rates for many types of cancer. For example, between 2004 and 2019, the risk of colon cancer recurring dropped by 31-68%. It is important to remember that only someone’s treatment team can assess an individual’s personal risk of cancer returning.

    For most types of cancer, the highest risk of cancer returning is within the first three years after entering remission. This is because any leftover cancer cells not killed by treatment are likely to start growing again sooner rather than later. Three years after entering remission, recurrence rates for most cancers decrease, meaning that every day that passes lowers the risk of the cancer returning.

    Every day that passes also increases the numbers of new discoveries, and cancer drugs being developed.

    What about second, unrelated cancers?

    Earlier this year, we learned Sarah Ferguson, Duchess of York, had been diagnosed with malignant melanoma (a type of skin cancer) shortly after being treated for breast cancer.

    Although details have not been confirmed, this is likely a new cancer that isn’t a recurrence or metastasis of the first one.

    Australian research from Queensland and Tasmania shows adults who have had cancer have around a 6-36% higher risk of developing a second primary cancer compared to the risk of cancer in the general population.

    Who’s at risk of another, unrelated cancer?

    With improvements in cancer diagnosis and treatment, people diagnosed with cancer are living longer than ever. This means they need to consider their long-term health, including their risk of developing another unrelated cancer.

    Reasons for such cancers include different types of cancers sharing the same kind of lifestyle, environmental and genetic risk factors.

    The increased risk is also likely partly due to the effects that some cancer treatments and imaging procedures have on the body. However, this increased risk is relatively small when compared with the (sometimes lifesaving) benefits of these treatment and procedures.

    While a 6-36% greater chance of getting a second, unrelated cancer may seem large, only around 10-12% of participants developed a second cancer in the Australian studies we mentioned. Both had a median follow-up time of around five years.

    Similarly, in a large US study only about one in 12 adult cancer patients developed a second type of cancer in the follow-up period (an average of seven years).

    The kind of first cancer you had also affects your risk of a second, unrelated cancer, as well as the type of second cancer you are at risk of. For example, in the two Australian studies we mentioned, the risk of a second cancer was greater for people with an initial diagnosis of head and neck cancer, or a haematological (blood) cancer.

    People diagnosed with cancer as a child, adolescent or young adult also have a greater risk of a second, unrelated cancer.

    What can I do to lower my risk?

    Regular follow-up examinations can give peace of mind, and ensure any subsequent cancer is caught early, when there’s the best chance of successful treatment.

    Maintenance therapy may be used to reduce the risk of some types of cancer returning. However, despite ongoing research, there are no specific treatments against cancer recurrence or developing a second, unrelated cancer.

    But there are things you can do to help lower your general risk of cancer – not smoking, being physically active, eating well, maintaining a healthy body weight, limiting alcohol intake and being sun safe. These all reduce the chance of cancer returning and getting a second cancer.

    Sarah Diepstraten, Senior Research Officer, Blood Cells and Blood Cancer Division, Walter and Eliza Hall Institute and Terry Boyle, Senior Lecturer in Cancer Epidemiology, University of South Australia

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • How can I tell if I am lonely? What are some of the signs?

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    Without even realising it, your world sometimes gradually gets smaller: less walking, fewer days in the office, cancelling on friends. Watching plans disintegrate on the chat as friends struggle to settle on a date or place for a catch-up.

    You might start to feel a bit flat or disconnected. Subtle changes in habit and mood take hold. Could you be … lonely?

    It’s not a label many of us identify with easily, especially if you know you’ve got friends, or are in a happy relationship.

    But loneliness can happen to us all from time to time – and identifying it is the first step to fixing it.

    gremlin/Getty Images

    So, what is loneliness?

    Loneliness is the distress we feel when our relationships don’t meet our needs – in quality or quantity.

    It’s not the same as being objectively alone (otherwise known as “social isolation”).

    You can feel deeply lonely even while surrounded by friends, or totally content on your own.

    Loneliness is subjective; many people don’t realise they’re lonely until the feeling becomes persistent.

    What are some of the signs to look for?

    You may feel a physical coldness, emptiness or hollowness (I’ve heard it described as feeling like you are missing an organ). Some research shows social pain is experienced similarly in the brain to physical pain.

    Behavioural signs may include:

    • changes in routine
    • trouble getting to sleep or staying asleep
    • changed appetite (maybe you’re eating more or less than you normally would, or have less variety in your diet)
    • withdrawing from plans you would usually enjoy (perhaps you’re skipping a regular exercise class, or going to shows or sports events less often).

    Emotionally, you may feel:

    • a persistent sadness
    • tired
    • disconnected
    • like you don’t belong, even when you are with others.

    You may also feel more sensitive to rejection or criticism.

    A man walks with a paper bag on his head.
    Sometimes, your world shrinks so gradually you barely notice it – until things get quite bad. francescoch/Getty Images

    But you’re not alone and you’re not broken.

    Loneliness is a normal response to disconnection.

    The late US neuroscientist John Cacioppo described loneliness as an evolutionary alarm system.

    In the past, being separated from your tribe meant danger and risk from predators, so our brains developed a way to push us back towards connection.

    The pain of loneliness is designed to keep us connected and safe.

    Why is it often hard to recognise loneliness?

    Sadly, there’s still a lot of stigma around admitting loneliness, especially for men.

    Many people resist identifying as lonely, or feel this marks them as a “loser”.

    But this silence can make the problem worse.

    When no one talks about it, it becomes harder to break the cycle of loneliness, and the stigma remains.

    While passing loneliness is normal, chronic or persistent loneliness can hurt our health.

    Research shows chronic loneliness is associated with:

    • depression
    • anxiety
    • weakened immunity
    • heart disease
    • earlier death.

    Loneliness can also become self-reinforcing. When loneliness feels normal, it can start to shape how you see the world: you expect rejection, withdraw more and the cycle deepens.

    The earlier you notice you’re lonely, the easier it is to break.

    But I’m in a relationship, have loads of friends and a rewarding job

    Yes, but you can still be lonely.

    Most of us need different kinds of relationships to thrive. It’s not about how many people you know, but whether you feel connected and have a meaningful role in these relationships.

    You may feel lonely even with strong friendships if you are lacking deeper connection, shared identity or a sense of community.

    This doesn’t mean you’re ungrateful, or a bad friend.

    It just means you need more or different kinds of connection.

    OK, I’ve realised I am lonely. Now what?

    Start by asking yourself: what kind of connection am I missing?

    Is it one-to-one friendships? A partner? Casual social interactions? A shared purpose or community?

    Then reflect on what’s helped you feel more connected in the past. For some, it’s joining a choir, a book club or a sports group. For others, it may be volunteering or just saying “yes” to small social moments, like chatting with your local barista or learning the name of the local butcher.

    If you’re still struggling, a psychologist can help with tailored strategies for building connection.

    The structural causes of loneliness

    It’s also important to remember loneliness is often not because of personal failings or overall mental health.

    My own research shows loneliness is often shaped by structural factors, such as poor planning in our local neighbourhood environments, financial inequality, work pressures, social norms, or even long-term effects of restrictions from the COVID pandemic.

    We are also learning more about how climate change can disrupt social connection and worsen loneliness due to, for example, higher temperatures or bushfires.

    Loneliness is normal, common, human and completely solvable.

    Start by noticing it in yourself and reach out if you can.

    Let’s start talking about it more, so others can feel less alone too.

    Marlee Bower, Senior Research Fellow, Matilda Centre for Research in Mental Health and Substance Use, University of Sydney

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Don’t let embarrassment stop you – talking about these anal cancer symptoms could save your life

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    Anal cancer doesn’t get a lot of attention. This may be because it’s relatively rare – anal cancer affects an estimated one to two Australians in every 100,000. As a comparison, melanomas affect around 70 in every 100,000 people.

    But it’s also likely due to embarrassment. Anal cancer is an abnormal growth in the cells lining the anus, the last few centimetres of the bowel. Many people feel awkward talking about this part of their body.

    So, when symptoms appear – such as bleeding or itchiness – they may delay speaking to a doctor. But it’s crucial to know what to look for, because if anal cancer is caught early the chances of treating it are much higher.

    Diagram showing the human gastrointestinal tract.
    The anus is the last few centimetres of the bowel. Designua/Shutterstock

    Do we know what causes it?

    Up to nine in ten anal cancers are caused by human papillomavirus (HPV), a sexually transmitted infection.

    HPV is common – more than 80% of people who have ever been sexually active will be infected at some point with a strain (there are more than 150).

    Most HPV strains won’t cause any problems. But some, particularly HPV16, are higher risk. Persistent infection can cause changes in the anal lining and this can progress to anal cancer. This can happen even if you don’t have anal sex.

    Vaccination against HPV is a highly effective method to reduce the risk of cancers related to HPV infection such as anal and cervical cancer.

    Since the national HPV vaccination program began in Australia in 2007, there has been a substantial drop in diseases linked to HPV (such as genital warts). While it’s too early to say, it is hoped that over time cancer rates will also fall due to vaccination.

    Other factors that increase your risk for anal cancer include:

    • being older
    • a history of smoking
    • a weakened immune system (for example from medication or HIV)
    • sexual activity (having anal sex or multiple sexual partners)
    • a history of cervical, vulval or vaginal cancer.
    Gloved hands write on a clipboard next to box of the vaccine Gardasil.
    Only some HPV strains are linked to cancer. wisely/Shutterstock

    What are the symptoms?

    Sometimes anal cancer doesn’t cause any symptoms. A doctor may instead detect the cancer visually during a colonoscopy or another examination.

    Other times, symptoms may include bleeding from the bottom (you might see blood on the toilet paper), a new anal lump, or feeling non-specific discomfort or itchiness in your anus.

    You may also have an unusual sensation that you can’t pass a stool as “fully” or easily as before.

    If you have any of these symptoms – particularly if they are new or getting worse – it is important to speak with your doctor.

    The symptoms of anal cancer can be very similar to common conditions such as haemorrhoids, so it’s best to get them checked by a doctor to get the diagnosis right.

    It’s understandable you might be embarrassed. But for doctors, this is all part of routine practice.

    sarkao/Shutterstock

    Catching it early improves your chances

    Survival rates are much better for anal cancer caught in the early stages.

    Around 90% of people diagnosed with stage one anal cancer will live five years or more. That drops to 60% if the diagnosis is made when the cancer has developed to stage three.

    The test may be as simple as a quick anal examination. Or it may require other investigations such as anoscopy (looking inside the bottom with a slim tube) or specialised ultrasounds or scans.

    Most tests involve only a small amount of discomfort or none at all. They can rule out anything serious, giving you peace of mind.

    If a cancer is detected, treatment usually involves radiotherapy, chemotherapy or surgery, or a combination.

    The bottom line

    If you need another reason to get symptoms checked out, here’s one: they could also indicate bowel cancer.

    Bowel cancer (also known as colon or colorectal cancer) is the fourth most common cancer diagnosed in Australia, and the second most common cause of cancer death, with similar symptoms such as bleeding from the bottom.

    So, it’s crucial to not to let awkwardness get in the way. Speak to your doctor if any symptoms concern you. Starting the conversation early could save your life.

    Suzanne Mahady, Gastroenterologist & Clinical Epidemiologist, Senior Lecturer, Monash University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Three-Bean Chili & Cashew Cream

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    A hearty classic with a twist! Delicious and filling and full of protein, fiber, and powerful phytonutrients (including heavy-hitters ergothioneine and lycopene), this recipe is also quite flexible, so you can always add in extra seasonal vegetables if you like (to get you started: cherry tomatoes in summer and sweet potato in fall are fine options)!

    You will need

    • 1 cup low-sodium vegetable stock (ideally you made it yourself from vegetable offcuts you kept in the freezer for this purpose, but if not, you should be able to find low-sodium stock cubes)
    • 1 can kidney beans, drained and rinsed
    • 1 can black beans, drained and rinsed
    • 1 can chickpeas, drained and rinsed
    • 2 cans chopped tomatoes
    • 1 onion, finely chopped
    • 1 carrot, diced
    • 2 celery sticks, chopped
    • 4 oz mushrooms, chopped
    • ½ bulb garlic, crushed
    • 2 tbsp tomato purée
    • 1 red chili pepper, finely chopped (multiply per your heat preferences)
    • 1 tbsp ground paprika
    • 1 tbsp black pepper, coarse ground
    • 2 tsp fresh rosemary (or 1 tbsp dried)
    • 2 tsp fresh thyme (or 1 tbsp dried)
    • 1 tsp ground cumin
    • ½ tsp MSG or 1 tsp low-sodium salt
    • Extra virgin olive oil

    For the cashew cream:

    • 6 oz cashews, soaked in kettle-hot water for at least 15 minutes
    • 1 tbsp nutritional yeast
    • 1 tsp lemon juice

    To serve:

    Method

    (we suggest you read everything at least once before doing anything)

    1) Heat some olive oil in a skillet and fry the onion for about 5 minutes, stirring as necessary.

    2) Add the garlic and chili and cook for a further 1 minute.

    3) Add the celery, carrot, and mushrooms and continue cooking for 1–2 minutes.

    4) Add everything else from the main section, taking care to stir well to distribute the seasonings evenly. Reduce the heat and allow to simmer for around 20 minutes, stirring occasionally.

    5) While you are waiting, drain the cashews, and add them to a high-speed blender with ½ cup (fresh) cold water, as well as the nutritional yeast and lemon juice. Blend on full power until smooth; this may take about 3 minutes, so we recommend doing it in 30-second bursts to avoid overheating the motor. You’ll also probably need to scrape it down the sides at least once. You can add a little more water if you want the cream to be thinner than it is appearing, but go slowly if you do.

    6) Serve with rice, adding a dollop of the cream and garnishing with parsley, with bread on the side if you like.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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