Aging Backwards – by Miranda Esmonde-White

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In this book, there’s an upside and a downside to the author’s professional background:

  • Upside: Miranda Esmonde-White is a ballet-dancer-turned-physical-trainer, and it shows
  • Downside: Miranda Esmonde-White is not a scientist, and it shows

She cites a lot of science, but she either does not understand it or else intentionally misrepresents it. We will assume the former. But as one example, she claims:

“for every minute you exercise, you lengthen your life by 7 minutes”

…which cheat code to immortality is absolutely not backed-up by the paper she cites for it. The paper, like most papers, was much more measured in its proclamations; “there was an association” and “with these conditions”, etc.

Nevertheless, while she misunderstands lots of science along the way, her actual advice is good and sound. Her workout programs really will help people to become younger by various (important, life-changing!) metrics of biological age, mostly pertaining to mobility.

And yes, this is a workout-based approach; we won’t read much about diet and other lifestyle factors here.

Bottom line: it has its flaws, but nevertheless delivers on its premise of helping the reader to become biologically younger through exercises, mostly mobility drills.

Click here to check out Aging Backwards, and age backwards!

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  • Are GMOs Good Or Bad For Us?

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    Unzipping Our Food’s Genes

    In yesterday’s newsletter, we asked you for your (health-related) views on GMOs.

    But what does the science say?

    First, a note on terms

    Technically, we (humans) have been (g)enetically (m)odifying (o)rganisms for thousands of years.

    If you eat a banana, you are enjoying the product of many generations of artificial selection, to change its genes to produce a fruit that is soft, sweet, high in nutrients, and digestible without cooking. The original banana plant would be barely recognizable to many people now (and also, barely edible). We’ve done similarly with countless other food products.

    So in this article, we’re going to be talking exclusively about modern genetic modification of organisms, using exciting new (ish, new as in “in the last century”) techniques to modify the genes directly, in a copy-paste fashion.

    For more details on the different kinds of genetic modification of organisms, and how they’re each done (including the modern kinds), check out this great article from Sciencing, who explain it in more words than we have room for here:

    Sciencing | How Are GMOs Made?

    (the above also offers tl;dr section summaries, which are great too)

    GMOS are outright dangerous (cancer risks, unknown risks, etc): True or False?

    False, so far as we know, in any direct* fashion. Obviously “unknown risks” is quite a factor, since those are, well, unknown. But GMOs on the market undergo a lot of safety testing, and have invariably passed happily.

    *However! Glyphosate (the herbicide), on the other hand, has a terrible safety profile and is internationally banned in very many countries for this reason.

    Why is this important? Because…

    • in the US (and two out of ten Canadian provinces), glyphosate is not banned
    • In the US (and we may hypothesize, those two Canadian provinces) one of the major uses of genetic modification of foodstuffs is to make it resistant to glyphosate
    • Consequently, GMO foodstuffs grown in those places have generally been liberally doused in glyphosate

    So… It’s not that the genetic modification itself makes the food dangerous and potentially carcinogenic (it doesn’t), but it is that the genetic modification makes it possible to use a lot more glyphosate without losing crops to glyphosate’s highly destructive properties.

    Which results in the end-consumer eating glyphosate. Which is not good. For example:

    ❝Following the landmark case against Monsanto, which saw them being found liable for a former groundskeeper, 46 year old Dewayne Johnson’s cancer, 32 countries have to date banned the use of Glyphosate, the key ingredient in Monsanto’s Roundup weed killer. The court awarded Johnson R4.2 billion in damages finding Monsanto “acted with malice or oppression”.❞

    Source: see below!

    You can read more about where glyphosate is and isn’t banned, here:

    33 countries ban the use of Glyphosate—the key ingredient in Roundup

    For the science of this (and especially the GMO → glyphosate use → cancer pipeline), see:

    Use of Genetically Modified Organism (GMO)-Containing Food Products in Children

    GMOs are extra healthy because of the modifications (they were designed for that, right?): True or False?

    True or False depending on who made them and why! As we’ve seen above, not all companies seem to have the best interests of consumer health in mind.

    However, they can be! Here are a couple of great examples:

    ❝Recently, two genome-edited crops targeted for nutritional improvement, high GABA tomatoes and high oleic acid soybeans, have been released to the market.

    Nutritional improvement in cultivated crops has been a major target of conventional genetic modification technologies as well as classical breeding methods❞

    Source: Drs. Nagamine & Ezura

    Read in full: Genome Editing for Improving Crop Nutrition

    (note, they draw a distinction of meaning between genome editing and genetic modification, according to which of two techniques is used, but for the purposes of our article today, this is under the same umbrella)

    Want to know more?

    If you’d like to read more about this than we have room for here, here’s a great review in the Journal of Food Science & Nutrition:

    Should we still worry about the safety of GMO foods? Why and why not? A review

    Take care!

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  • What Your Hands Can Tell You About Your Health

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    Dr. Siobhan Deshauer tells us what our hands say about our health—she’s not practicing palmistry though; she’s a rheumatologist, and everything here is about clinical signs of health/disease.

    The signs include…

    “Spider fingers” (which your writer here has; I always look like I’m ready to cast a spell of some kind), and that’s really the medical name, or arachnodactyly for those who like to get Greek about it. It’s about elongated digits. Elongated other bones too, typically, but the hands are where it’s most noticeable.

    The tests:

    • Make a fist with your thumb inside (the way you were told never to punch); does your thumb poke out the side notably past the edge of your hand, unassisted (i.e., don’t poke it, just let it rest where it goes to naturally)?
    • Take hold of one of your wrists with the fingers of the other hand, wrapping them around. If they reach, that’s normal; if there’s a notable overlap, we’re in Spidey-territory now.

    If both of those are positive results for you, Dr. Deshauer recommends getting a genetic test to see if you have Marfan syndrome, because…

    Arachnodactyly often comes from a genetic condition called Marfan syndrome, and as well as the elongated digits of arachnodactyly, Marfan syndrome affects the elastic fibers of the body, and comes with the trade-off of an increased risk of assorted kinds of sudden death (if something goes “ping” where it shouldn’t, like the heart or lungs).

    But it can also come from Ehlers-Danlos Syndrome!

    EDS is characterized by hypermobility of joints, meaning that they are easily flexed past the normal human limit, and/but also easily dislocated.

    The tests:

    • Put your hand flat on a surface, and using your other hand, see how far back your fingers will bend (without discomfort, please); do they go further than 90°?
    • Can you touch your thumb to your wrist* (on the same side?)

    *She says “wrist”; for this arachnodactylic writer here it’s halfway down my forearm, but you get the idea

    For many people this is a mere quirk and inconvenience, for others it can be more serious and a cause of eventual chronic pain, and for a few, it can be very serious and come with cardiovascular problems (similar to the Marfan syndrome issues above). This latter is usually diagnosed early in life, though, such as when a child comes in with an aneurysm, or there’s a family history of it. Another thing to watch out for!

    Check out the video for more information on these, as well as what our fingerprints can mean, indicators of diabetes (specifically, a test for diabetic cheiroarthropathy that you can do at home, like the tests above), carpal tunnel syndrome, Raynaud phenomenon, and more!

    She covers 10 main medical conditions in total:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to read more?

    Take care!

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  • Full Body Stretches (Without Getting On The Floor)

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    When it comes to exercise, do you love getting down on the floor? No?

    If you don’t, then mobility coach Alisa Szyman has just the thing for you:

    Stick to this

    This routine uses a dowel rod (or broomstick) to unlock your hips, spine, and shoulders. We’ll be doing warm-up, mobility, and active stretching. Here’s what it looks like, step-by-step:

    • Warm up:
      • Hold the dowel overhead and lower it to meet your lifted knee, alternating sides.
      • Put the dowel across your upper back, and rotate your torso from side to side with your hips facing forwards.
      • With the dowel behind you, make controlled torso circles forwards and backwards to loosen your mid-back.
      • If you take your time and prioritize good form, you should feel the difference (in a good way!) before proceeding to the exercises below.
    • Good morning: with the dowel behind your head, hinge forwards from your hips while keeping your spine long and chest open, then return upright.
    • Hamstring sweep: with a wide stance and soft knees, hinge at your hips and sweep your chest in a smooth arc from one side to the other, stretching your hamstrings and engaging your core.
    • Shoulder mobility: hold the dowel in one hand and rotate it behind your back to the other hand, passing it around your body slowly and with good, steady control.
    • Wrist stretch: hold the dowel in front with both hands; twist your wrists one way, then the other, feeling the stretch through your wrists, shoulders, and arms.
    • Lateral squat & twist: hold the dowel at hip level, shift into a side squat, twist your torso towards your bent leg, lean forwards slightly, and reach the dowel towards the floor.
    • Forward fold: with the dowel behind your back, hinge forwards from your hips, fold your torso towards the floor as your arms lift up and over your head, then return to standing.
    • Side bends: with one end of the dowel on the floor, and the other arm overhead reaching to the side, bend through your torso to stretch your the side of your body.
    • Spine rotation (lift and twist): hold the dowel in front with wide arms, lift one arm and rotate your torso towards that side, stretching your shoulder, chest, and upper back.
    • Spine rotation (parallel hold): with the dowel held straight at hip level, lift it to shoulder height as you rotate your torso to one side, keeping the dowel parallel to the floor, then return to center.
    • Hips, glutes & balance: using the dowel for support, lift your knee, hinge forwards from your hips, extend your back leg while lowering your chest, then return to the start to do the other side.
    • Hip abduction & curtsy lunge: using the dowel for balance again, lift your leg out to the side, then step it diagonally behind you into a curtsy lunge, returning to standing before repeating.
    • Sumo squat: with a wide stance with toes slightly out, hold the dowel and lift your arms parallel to the floor, lowering into a squat while keeping your chest tall, stretching and strengthening your inner thighs and groin as you do.
    • Full body stretch: with the dowel overhead and your arms straight, reach upwards as you inhale, then exhale as you fold forwards, relaxing your back; repeat with gentle side-to-side swaying.

    For more detail plus visual demonstrations that make it much easier than it might sound, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    3 Standing Abs Exercises You’ll Actually Feel Tomorrow

    Take care!

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  • The Medicinal Properties Of Bay Leaves

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    The humble bay leaf has more uses than just culinary!

    How about for hair growth?

    Popularly recommended on social media with the promise of long and glowing hair… Guess how many scientific studies back up this claim!

    If you guessed zero, you guessed correctly. At least, we were not able to find any. In fact, the only paper on the entirety of PubMed (a large online database of available scientific literature from most, if not all, reputable scientific journals) to return a hit for the search string “bay leaf hair growth” was this one:

    Suppression of Propionibacterium acnes-Induced Skin Inflammation by Laurus nobilis Extract and Its Major Constituent Eucalyptol

    You may notice that that has nothing to do with hair growth, and rather returned the hit because the acne bacteria are known to “proliferate within sebum-blocked skin hair follicles”.

    So let’s talk about that instead:

    Against acne & skin inflammation

    Well, for that, it works! The research that we mentioned above concluded that:

    ❝LNE significantly suppressed the expression of P. acnes-mediated proinflammatory cytokines, such as IL-1β, IL-6, and NLRP3. We also found that LNE inhibited the inflammatory transcription factor NF-κB in response to P. acnes. In addition, eucalyptol, which is the main constituent of LNE, consistently inhibited P. acnes-induced inflammatory signaling pathways. Moreover, LNE significantly ameliorated P. acnes-induced inflammation in a mouse model of acne. We suggest for the first time that LNE hold therapeutic value for the improvement of P. acnes-induced skin inflammation.❞

    LNE = Laurus nobilis extract, i.e. bay leaf extract

    Now, that’s all about acne-induced skin inflammation, but what about other kinds?

    Against inflammation in general

    Bay leaves have an abundance of antioxidant polyphenols, and what’s good against oxidation is good against inflammation. For example:

    Laurus nobilis leaf extract controls inflammation by suppressing NLRP3 inflammasome activation

    That anti-inflammatory action is more than skin-deep though, because…

    Against IBD / ulcerative colitis

    It’s good for the gut, too, for example in this study (with mice, but the bacteria affected are the same as we have), which found:

    ❝…bay leaves showed the best treatment effects on gut microbiota compositions; promoting the growth of Bifidobacteria and Lactobacillus in addition to producing high butyric acid levels. Meanwhile, the number of Clostridium and sulfate-reducing bacteria was significantly reduced. Conclusively, consuming bay leaves brought significant colon health benefits other than stimulating appetite for a better taste.❞

    Read in full: Anti‐inflammatory effects of bay laurel (Laurus nobilis L.) towards the gut microbiome in dextran sodium sulfate induced colitis animal models

    Note that all of those gut-related changes are beneficial to us, increasing things that are best increased, and reducing things that are best reduced.

    Against diabetes

    It’s good for the blood—and for the heart, but more on that later. First, about diabetes:

    ❝All three levels of bay leaves reduced serum glucose with significant decreases ranging from 21 to 26% after 30 d.

    Total cholesterol decreased, 20 to 24%, after 30 days with larger decreases in low density lipoprotein (LDL) cholesterol of 32 to 40%. High density lipoprotein (HDL) cholesterol increased 29 and 20% in the groups receiving 1 and 2 g of bay leaves, respectively. Triglycerides also decreased 34 and 25% in groups consuming 1 and 2 g of bay leaves, respectively, after 30 d. There were no significant changes in the placebo group.

    In summary, this study demonstrates that consumption of bay leaves, 1 to 3 g/d for 30 days, decreases risk factors for diabetes and cardiovascular diseases and suggests that bay leaves may be beneficial for people with type 2 diabetes.❞

    Again, all those changes are good:

    Bay Leaves Improve Glucose and Lipid Profile of People with Type 2 Diabetes

    Good for the heart

    This one’s quite straight forward. Bay leaf tea is indeed good for the heart,

    Of course, even that latter is also good for the heart literally, just, indirectly, by reducing anxiety and stress, thus indirectly benefiting the heart itself.

    But even before that, it’s already very directly beneficial to cardiovascular health, per its significant improvements to the lipid profile.

    Anything else?

    So much else, but there’s only so much we can feature in one day, so if you’d like to learn more, we recommend this very comprehensive paper:

    Chromatography analysis, in light of vitro antioxidant, antidiabetic, antiobesity, anti-inflammatory, antimicrobial, anticancer, and three-dimensional cancer spheroids’ formation blocking activities of Laurus nobilis aromatic oil from Palestine

    …which discusses many benefits in considerable detail, including…

    ❝The LN leaves have various biological activities, such as antioxidant, wound healing, antibacterial, analgesic, and anti-inflammatory activities. However, oxidative stress, cancer, diabetes, microbial infections, and inflammatory diseases are closely linked. The objective of this research is to characterize Laurus nobilis (LN) aromatic oil (AO) and evaluate its antioxidant, antidiabetic, antiobesity, antimicrobial, and antimutagenic bioactivities.

    The plant AO showed potent antioxidant activity (IC50 = 2.2 ± 1.38) and has moderate anti-amylase (IC50 = 60.25 ± 1.25), anti-glucosidase (IC50 = 131.82 ± 0.1), and antilipase (IC50 = 83.17 ± 0.06) activities.

    Moreover, LNAO showed potent antimicrobial activity against Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, Proteus vulgaris (MICs = 1.56 µg/mL), methicillin-resistant Staphylococcus aureus (MRSA) (MIC = 3.125 µg/mL) and Candida albicans (MIC = 0.195 µg/mL). The cytotoxicity results demonstrated that at a concentration of 1 mg/mL, LNAO has potent breast cancer (MCF-7), and hepatocellular carcinoma (Hep 3B) cancer cells inhibitory activities of 98% and 95%, respectively.

    Importantly, we are the first to show that LNAO significantly hinders hepatocellular carcinoma spheroids’ formation capacity in a 3D model.

    These results show that LNAO is a promising natural source with powerful antioxidant, antidiabetic, anticancer, and antimicrobial activities that could be exploited in the future to treat a variety of diseases.❞

    Want to try some?

    We don’t sell it, but you can buy leaves from your local supermarket and make bay leaf tea, or alternatively, if you prefer essential oil form, here for your convenience is an example product on Amazon 😎

    Enjoy!

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  • 5 Movements You’ll Wish You’d Known Sooner

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    Alisa Szyman, mobility coach, shows us why:

    Best for mobility, best against pain

    These movements are what’s needed for good mobility (range of motion, flexibility, strength, stability) while also being a top-tier way of combatting pain, due to what they do for the body’s natural functions.

    Specifically, the exercises are intended to build on one another, beginning with neck stability, then restoring upper-back rotation, activating your glutes, improving hip control, and finally reducing hamstring and posterior-chain tightness:

    • Chin tucks: stand tall, bring your chin slightly forwards, then push it straight back to create a double chin while keeping your head level, and follow with slow shoulder shrugs by lifting your shoulders towards your ears and lowering them under control.
    • Quadruped thoracic rotations: start on all fours with one hand on the floor and the other extended to the side, rotate through your upper back to lift the arm towards the ceiling while following it with your eyes, then return to the start position.
    • Glute bridges: lie on your back with your knees bent and feet flat, squeeze your glutes before lifting your hips, hold briefly at the top, then lower slowly while keeping the effort in your glutes rather than your lower back.
    • Hip CARs (controlled articular rotations): stand or kneel, lift one knee and slowly move your hip through its fullest circular range while keeping your spine and upper body still, then repeat in both directions on each side.
    • Sciatic nerve flossing: lie on your back with one knee bent and your foot flat on the floor, raise the other leg towards the ceiling, then gently flex and point your foot or make slow ankle circles, to glide the sciatic nerve through its range of motion.

    For more on all of this plus visual demonstrations, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    Best Mobility Drills For Posture & Pain Relief

    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

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  • Reinventing Your Life – by Dr. Jeffrey Young & Dr. Janet Klosko

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    This book is quite unlike any other broadly-CBT-focused books we’ve reviewed before. How so, you may wonder?

    Rather than focusing on automatic negative thoughts and cognitive distortions with a small-lens focus on an immediate problem, this one zooms out rather and tackles the cause rather than the symptom.

    The authors outline eleven “lifetraps” that we can get stuck in:

    1. Abandonment
    2. Mistrust & abuse
    3. Vulnerability
    4. Dependence
    5. Emptional deprivation
    6. Social exclusion
    7. Defectiveness
    8. Failure
    9. Subjugation
    10. Unrelenting standards
    11. Entitlement

    They then borrow from other areas of psychology, to examine where these things came from, and how they can be addressed, such that we can escape from them.

    The style of the book is very reader-friendly pop-psychology, with illustrative (and perhaps apocryphal, but no less useful for it if so) case studies.

    The authors then go on to give step-by-step instructions for dealing with each of the 11 lifetraps, per 6 unmet needs we probably had that got us into them, and per 3 likely ways we tried to cope with this using maladaptive coping mechanisms that got us into the lifetrap(s) we ended up in.

    Bottom line: if you feel there’s something in your life that’s difficult to escape from (we cannot outrun ourselves, after all, and bring our problems with us), this book could well contain the key that you need to get out of that cycle.

    Click here to check out “Reinventing Your Life” and break free from any lifetrap(s) of your own!

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