10 Ways To Delay Aging

10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

This is Dr. Colin Rose; he is a Senior Associate of the Royal Society of Medicine. He’s also a main contributor to EduScience, a program funded by the E.U. which is designed to enhance the teaching and learning of science in schools in Europe.

His most recent work has been about aging—and how to delay it. We also reviewed his latest book, here:

Delay Ageing – by Dr. Colin Rose

So, what does he want us to know? The key lies in his compilation of ten ways in which we age on a cellular level, and what we can to do slow each one of those:

Damage to DNA accumulates

While DNA can get damaged without any external stimulus to cause that, there are a lot of modifiable factors that we can do to reduce DNA damage. The list is easy: if it causes cancer, it causes aging.

Thus, check out: Stop Cancer 20 Years Ago

Cells become senescent

Our cells are replaced all the time; some sooner than others, but all of them at some point. The problem occurs when cells are outliving their usefulness. If a cell becomes completely immortal, that is cancer, but happily most don’t. Nevertheless, having senescent (aging) cells in the body means that those senescent cells are what get copied forwards by mitosis, and our DNA becomes like a photocopy of a tattered old photocopy of a tattered old photocopy. Which, needless to say, is not good for our health. So, the best thing to do is to kill them earlier:

Yes, really: Fisetin: The Anti-Aging Assassin

Mitochondria become dysfunctional

Without properly functional mitochondria, no living human cell can do its job properly.

Options: 7 Ways To Boost Mitochondrial Health To Fight Disease

Beneficial genes are switched off, harmful genes are on

It’s easy to think of our genes as being immutable, but epigenetics means that our environment (amongst other factors) can mean that our gene expression changes.

Imagine it this way: your genes are a set of instructions for your body. However, your body will act or not on those instructions, depending on other factors. Hormones often play a big part in this; for example sex hormones tell the body which set of genetic instructions to read (and thus what kind of body to build/rebuild), and cortisol or oxytocin can tell the body which set of contingency plans to activate or suppress (respectively). A milder example is gray hair; genes have the program for it, but many other factors inform the body when, if, and how to do it.

Of more concern when it comes to aging is what goes on with more critical systems, such as the brain, in which the aforementioned DNA damage can cause unhelpful instructions to get interpreted, resulting in epigenetic changes that in turn facilitate age-related degeneration.

As to what can be done, see : Klotho: Unzipping The Genes Of Aging?

Stem cells become exhausted

Stem cells can become different kinds of cells, and thus they’re very useful for maintaining a healthy body. However, they get depleted with age. We can slow down the rate of loss, though; for example, intermittent fasting can help:

Per Dr. Li’s 5 Ways To Beat Cancer (And Other Diseases)

And for more detail, see:

Doctor’s Tip: Regeneration (stem cells) — one of your body’s five defense systems

(complete with lists of foods to eat or avoid for stem cell health)

Cells fail to communicate properly

Cells need to talk to each other constantly, to continue doing their jobs. We are one big organism, after all, and not a haphazard colony of the countless cells that constitute such. However, cell signalling gets worse with age, which in turn precipitates others age-related problems. Fortunately, there are nutrients that can improve cellular communication.

For example: PS, We Love You ← this is about phosphatidylserine, also called “PS”

Telomeres become shorter

These protective caps on our DNA suffer the wear-and-tear so that our DNA doesn’t have to. However, as they get shorter, the DNA can start suffering damage. For this reason, telomere length is considered one of the most “Gold Standard” markers of cellular aging.

Here’s what can be done for that: The Stress Prescription (Against Aging!)

The body fails to sense nutritional intake properly

This is mostly about insulin signalling (though problems can occur in other systems too, but we only have so much room here), so it’s important to take care of that.

See: Turn Back The Clock On Insulin Resistance

Proteins accumulate errors

This is due to DNA damage, of course, but there are specific things that can reduce protein error accumulation; see for example:

A quick fix – preventing protein errors extends lifespan

See also: Rapamycin Can Slow Aging By 20% (But Watch Out)

The microbiome becomes unbalanced

We at 10almonds often mention that gut health affects pretty much every other kind of health, and it’s true for aging as well. So, take care of that microbiome!

Here’s a primer: Gut Health 101

Want to know more about delaying aging beyond the cellular level?

Check out: Age & Aging: What Can (And Can’t) We Do About It?

Take care!

Don’t Forget…

Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

Recommended

  • Dial Down Your Pain
  • The Breathing Cure – by Patrick McKeown
    “Breath’s Impact on Health: Learn how The Breathing Cure delves into breathing’s role in illness and offers science-backed improvement strategies.”

Learn to Age Gracefully

Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Uric Acid’s Extensive Health Impact (And How To Lower It)

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Uric Acid’s Extensive Health Impact (And How To Lower It)

    This is Dr. David Perlmutter. He’s a medical doctor, and a Fellow of the American College of Nutrition. He’s a member of the Editorial Board for the Journal of Alzheimer’s Disease, and has been widely published in many other peer-reviewed journals.

    What does he want us to know?

    He wants us to know about the health risks of uric acid (not something popularly talked about so much!), and how to reduce it.

    First: what is it? Uric acid is a substance we make in our own body. However, unlike most substances we make in our body, we have negligible use for it—it’s largely a waste product, usually excreted in urine.

    However, if we get too much, it can build up (and crystallize), becoming such things as kidney stones, or causing painful inflammation if it shows up in the joints, as in gout.

    More seriously (unpleasant as kidney stones and gout may be), this inflammation can have a knock-on effect triggering (or worsening) other inflammatory conditions, ranging from non-alcoholic fatty liver disease, to arthritis, to dementia, and even heart problems. See for example:

    How can we reduce our uric acid levels?

    Uric acid is produced when we metabolize purine nucleotides, which are found in many kinds of food. We can therefore reduce our uric acid levels by reducing our purine intake, as well as things that mess up our liver’s ability to detoxify things. Offsetting the values for confounding variables (such as fiber content, or phytochemicals that mitigate the harm), the worst offenders include…

    Liver-debilitating things:

    • Alcohol (especially beer)
    • High-fructose corn syrup (and other fructose-containing things that aren’t actual fruit)
    • Other refined sugars
    • Wheat / white flour products (this is why beer is worse than wine, for example; it’s a double-vector hit)

    Purine-rich things:

    • Red meats and game
    • Organ meats
    • Oily fish, and seafood (great for some things; not great for this)

    Some beans and legumes are also high in purines, but much like real fruit has a neutral or positive effect on blood sugar health despite its fructose content, the beans and legumes that are high in purines, also contain phytochemicals that help lower uric acid levels, so have a beneficial effect.

    Eggs (consumed in moderation) and tart cherries have a uric-acid lowering effect.

    Water is important for all aspects of health, and doubly important for this.

    Hydrate well!

    Lifestyle matters beyond diet

    The main key here is metabolic health, so Dr. Perlmutter advises the uncontroversial lifestyle choices of moderate exercise and good sleep, as well as (more critically) intermittent fasting. We wrote previously on other things that can benefit liver health:

    How To Unfatty A Fatty Liver

    …in this case, that means the liver gets a break to recuperate (something it’s very good at, but does need to get a chance to do), which means that while you’re not giving it something new to do, it can quickly catch up on any backlog, and then tackle any new things fresh, next time you start eating.

    Want to know more about this from Dr. Perlmutter?

    You might like his article:

    An Integrated Plan for Lowering Uric Acid ← more than we had room for here; he also talks about extra things to include in your diet/supplementation regime for beneficial effects!

    And/or his book:

    Drop Acid: The Surprising New Science of Uric Acid―The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health

    …on which much of today’s main feature was based.

    Take care!

    Share This Post

  • The Secret Easy Tips to Loosen Your Hips In 10 Minutes

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Stiff hips can often cause discomfort, and ultimately back pain because of how one thing relies on the other as its seat. However, there are ways to improve it without taking years to get to where you want to be:

    One bit at a time

    Warm up and massage:

    • Massage the front and back of the thighs to loosen tight muscles.
    • Use your body weight for effective massaging.
    • Relax and breathe slowly while massaging.

    Vary your stretches:

    • Perform a seated butterfly stretch, but avoid overexertion.
    • Move knees gently within a comfortable range of motion.
    • Perform stretches like placing one foot on the opposite knee or holding legs to open hips.
    • Stretch the hips while lying on the floor with bent knees.

    And now for the “magic move”: lie on your stomach, bend one knee, and gently rock to loosen hip stiffness.

    Generally speaking, for most stretches one can usually stretch further on one side at once, than both at the same time. So, leverage this in your flexibility training, to get each side of your body accustomed to going that bit further. Then, when your body is comfortable with that, put it together.

    For more on all of this plus visual demonstrations, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    How Tight Are Your Hips? Test (And Fix!) With This

    Take care!

    Share This Post

  • How To Know When You’re Healing Emotionally

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    The healing process can be humbling but rewarding, leading to deep fulfillment and inner peace. Discomfort in healing can be part of growth and self-integration. Because of that, progress sometimes looks and/or feels like progress… And sometimes it doesn’t. Here’s how to recognize it, though:

    Small but important parts of a bigger process

    Nine signs indicating you are healing:

    1. Allowing emotions: you acknowledge and process both negative and positive emotions instead of suppressing them.
    2. Improved boundaries: you improve at expressing and maintaining boundaries, overcoming fear of rejection, guilt, and shame.
    3. Acceptance of past: you accept difficult past experiences and their impact, reducing their hold over you.
    4. Less reactivity: you become less reactive and more thoughtful in responses, practicing emotional self-regulation.
    5. Non-linear healing: you understand that healing involves ups and downs and isn’t a straightforward journey.
    6. Stepping out of your comfort zone: you start taking brave steps that previously induced fear or anxiety.
    7. Handling disappointments: you accept setbacks and respond to them healthily, without losing motivation.
    8. Inner peace: you develop a sense of wholeness, and forgiveness for yourself and others, reducing self-sabotage.
    9. Welcoming support: you become more open to seeking and accepting help, moving beyond pride and shame.

    In short: healing (especially the very first part: accepting that something needs healing) can be uncomfortable but lead to much better places in life.  It’s okay if healing is slow; everyone’s journey is different, and doing your best is enough.

    For more on each of these, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    Why You Can’t Just “Get Over” Trauma

    Take care!

    Share This Post

Related Posts

  • Dial Down Your Pain
  • Who Will Take Care of Me When I’m Old? – by Joy Loverde

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Regular readers of 10almonds will know we’ve written before about how isolation kills (in numerous ways), and this book tackles that in much greater length and depth than we ever have room for here.

    Specifically, she talks about preparing for medical and related (financial, living will in case of dementia, housing, etc) considerations down the line, with checklists and worksheets and such to make it easy, and help you make sure it actually gets done.

    She also talks about creating a support network, from scratch if necessary (“foraging a family”), so that even if you will now be prepared to handle things alone, you’ll become a lot less likely to need to do so.

    Unlike many books of this genre, she also covers managing your mortality; that “just shoot me” is not a plan, and what lessons can be learned from the dying to make our own last years the best they can be.

    The style is upbeat and positive in outlook; less “prepare for doom” and more “get ready to do things right”, and it’s worth mentioning that the format is particularly helpful, outlining objectives towards the beginning of each chapter, and additional resources at the end of each chapter.

    Over on Amazon, most of the reviews that contain any criticism are some manner of “I’m in my 70s and wish I had read this sooner”. Still, better late than never.

    Bottom line: if you do not have an overabundance of support network around you, then this is an important book to read and to put into action.

    Click here to check out Who Will Take Care Of Me When I’m Old, and safeguard your own health & happiness for years to come!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Fennel vs Artichoke – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing fennel to artichoke, we picked the artichoke.

    Why?

    Both are great! But artichoke wins on nutritional density.

    In terms of macros, artichoke has more protein and more fiber, for only slightly more carbs.

    Vitamins are another win for artichoke, boasting more of vitamins B1, B2, B3, B5, B6, B9, and choline. Meanwhile, fennel has more of vitamins A, E, and K, which is also very respectable but does allow artichoke a 6:3 lead.

    In the category of minerals, artichoke has a lot more copper, iron, magnesium, manganese, and phosphorus, while fennel has a little more calcium, potassium, and selenium.

    One other relevant factor is that fennel is a moderate appetite suppressant, which may be good or bad depending on your food-related goals.

    All in all though, we say the artichoke wins by virtue of its greater abundance of nutrients!

    Want to learn more?

    You might like to read:

    What Matters Most For Your Heart? ← appropriately enough, with fennel hearts and artichoke hearts!

    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Top 8 Habits Of The Top 1% Healthiest Over-50s

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Will Harlow, over-50s specialist physio, compiled some stats from over a thousand over-50s clients:

    Checklist

    The findings:

    1. Consistency: the healthiest individuals practised some kind(s) of health habit daily. Consistency was emphasized as more important than perfection.
    2. Resistance training: 75% of the sample engaged in resistance training for better mobility, strength, and mental health. Not all used gyms; some used household objects like bags of books or resistance bands.
    3. Walking: everyone walked at least 6,000 steps per day, often briskly. Walking speed, not just step count, made a significant difference
    4. Purpose: most participants (bearing in mind that 80% of the total sample were retired) engaged in purposeful activities like volunteering, joining groups, or writing. Having a sense of purpose correlated with longer and healthier lives.
    5. Flexible dieting: participants paid attention to their eating without strictly following specific diets. Portion size discipline and consistency (eating well 90% of the time) were key.
    6. Mobility: they worked on joint stiffness with regular mobility and stretching routines. And, importantly, they do not accept stiffness as inevitable.
    7. Social engagement: they maintained at-least-weekly social contact (e.g. clubs, family meetups, outings). Social isolation, in contrast, was linked to severe health risks like dementia and early death.
    8. Positivity: participants maintained a positive attitude despite hardships, focussing on the things they could control. Broader scientific consensus supports the premise that a positive outlook improves health and longevity.

    10almonds note: we’re curious as to how causality was established in some of these, since (for example) it could easily be that someone who is in better health will more readily walk more quickly, meaning that a higher walking speed was not necessarily such a causative factor in good health, but rather a result thereof. Of course, there may also be a degree of two-way causality, but still, we like good science and there seem to be some leaps of logic here that have otherwise gone unacknowledged.

    This does not take away from the fact that those eight things are most certainly good things to be doing for one’s health, all the same.

    For more on each of these, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    The Most Anti Aging Exercise

    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails: