The Immunostimulant Superfood

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Eat These Greens!

Chlorella vulgaris, henceforth “chlorella”, is a simple green algae that has a lot of health benefits.

Note: most of the studies here are for Chlorella vulgaris specifically. However, some are for other species of the Chlorella genus, of which Chlorella vulgaris is by far the most common, hence the name (vulgaris = common). The relevant phytochemical properties appear to be the same regardless.

Superfood

While people generally take it as a supplement rather than a food item in any kind of bulk, it is more than 50% protein and contains all 9 essential amino acids.

As you might expect of a green superfood, it’s also full of many antioxidants, most of them carotenoids, and these pack a punch, for example against cancer:

Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells

It also has a lot of vitamins and minerals, and even omega-3.

Which latter also means it helps improve lipids and is thus particularly…

Heart healthy

❝Daily consumption of Chlorella supplements provided the potential of health benefits reducing serum lipid risk factors, mainly triglycerides and total cholesterol❞

~ Dr. Na Hee Ryu et al.

Read more: Impact of daily Chlorella consumption on serum lipid and carotenoid profiles in mildly hypercholesterolemic adults: a double-blinded, randomized, placebo-controlled study

Its heart-healthy benefits don’t stop at lipids though, and include blood pressure management, as in this study that found…

❝GABA-rich Chlorella significantly decreased high-normal blood pressure and borderline hypertension, and is a beneficial dietary supplement for prevention of the development of hypertension. ❞

~ Dr. Morio Shimada et al.

Read more: Anti-hypertensive effect of gamma-aminobutyric acid (GABA)-rich Chlorella on high-normal blood pressure and borderline hypertension in placebo-controlled double blind study

About that GABA, if you’re curious about that, check out:

GABA Against Stress, Anxiety, & More

May remove heavy metals

We’re going with “may” for this one as we could only find animal studies so far (probably because most humans don’t have megadoses of heavy metals in them, which makes testing harder).

Here’s an example animal study, though:

Enhanced elimination of tissue methyl mercury in [Chlorella]-fed mice

Immunostimulant

This one’s clearer, for example in this 8-week study (with humans) that found…

❝Serum concentrations of interferon-γ (p<0.05) and interleukin-1β (p<0.001) significantly increased and that of interleukin-12 (p<0.1) tended to increase in the Chlorella group.

The increments of these cytokines after the intervention were significantly bigger in the Chlorella group than those in the placebo group. In addition, NK cell activities (%) were significantly increased in Chlorella group, but not in Placebo group.

The increments of NK cell activities (%) were also significantly bigger in the Chlorella group than the placebo group.

Additionally, changed levels of NK cell activity were positively correlated with those of serum interleukin-1β (r=0.280, p=0.047) and interferon-γ (r=0.271, p<0.005).❞

~ Dr. Jung Hyun Kwak et al.

tl;dr = it boosts numerous different kinds of immune cells

Read more: Beneficial immunostimulatory effect of short-term Chlorella supplementation: enhancement of natural killer cell activity and early inflammatory response (randomized, double-blinded, placebo-controlled trial)

PS, if you click though to the study, you may be momentarily alarmed by the first paragraph of the abstract that says “However, there were no direct evidences for the effect of Chlorella supplementation on immune/inflammation response in healthy humans“

this is from the “Background” section of the abstract, so what they are saying is “before we did this study, nobody had done this yet”.

So, be assured that the results are worthwhile and compelling.

Is it safe?

Based on the studies, it has a good safety profile. However, as it boosts the immune system, you may want to check with your doctor if you have an autoimmune disorder, and/or you are on immunosuppressants.

And in general, of course always check with your doctor/pharmacist if unsure about any potential drug interactions.

Want some?

We don’t sell it, but here for your convenience is an example product on Amazon

Enjoy!

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  • Worried after sunscreen recalls? Here’s how to choose a safe one

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Most of us know sunscreen is a key way to protect areas of our skin not easily covered by clothes from excessive ultraviolet (UV) radiation.

    But it’s been a rough year for sunscreens.

    In June, testing by Choice identified 16 products on Australian shelves that don’t provide the SPF protection they claimed.

    In July, the Therapeutic Goods Administration (TGA) released a review recommending the amount of certain chemical ingredients allowed in sunscreens should be lowered.

    Since then, several other sunscreens have been recalled or are under review, either due to manufacturing defects or concerns about poor SPF cover.

    All this has left many of us feeling confused about which sunscreens are safe, effective and do what they say on the label.

    Here’s what you need to know so you can stay safe this summer.

    Kindel Media/Pexels

    The good news first

    There’s very little evidence sunscreens cause cancer and plenty of evidence they prevent skin cancer.

    This is vital in Australia, where two in three people will get skin cancer at some point in their lives.

    One randomised controlled trial in Queensland, run over four and a half years between 1992 and 1996, asked 1,621 people to either use sunscreen every day or continue their usual use (usually one or two days a week or not at all).

    It found using sunscreen every day reduced the numbers of squamous cell carcinomas by 40%, compared to the group that didn’t change their habits. Ten years after the study, the number of invasive melanomas was reduced by 73% in the daily sunscreen group.

    Significantly, this study was conducted in the 90s using SPF 16 sunscreen. Modern sunscreens are expected to routinely provide SPF 30+ or 50+ protection.

    Companies should provide the SPF levels they’re advertising. But this research shows even sub-par sunscreen (by modern standards) provides significant protection with daily use.

    Making sure SPF claims stack up

    In Australia, the TGA regulates how SPF is assessed in sunscreens, but doesn’t do the testing itself. Instead, companies perform or outsource the testing, which must be done on human skin, and provide the TGA with their results.

    But when Choice independently tested 20 Australian sunscreens, it found 16 did not meet the SPF factor on the label.

    An ABC investigation pinpointed two potential sources of the problems: a poor quality base ingredient manufactured by Wild Child Laboratories, and suspicious SPF testing data from Princeton Consumer Research, which many of the brands relied on.

    The TGA has since recommended that people stop using 21 products that contain the Wild Child base, listed here.

    What about the chemical ingredients?

    The TGA regularly reviews scientific research to make sure Australian sunscreens keep up with advances in safety and effectiveness. To be sold in Australia, sunscreens must use active ingredients from a specific list, limited at maximum concentrations.

    July’s safety review found evidence that two permitted ingredients – homosalate and oxybenzone – can cause hormone disruptions in some animals exposed to high doses for a long time. These doses were far higher than someone would be exposed to from sunscreen – even at the maximum usage – thanks to the TGA’s ingredient limits.

    Still, chemical risks are managed strictly. The amount absorbed during consistent, high-dose sunscreen use, year-round, must be less than 1% of the dose known to cause problems in animals.

    The new results suggest that absorption could go over this “margin of safety”. So the TGA has recommended the amount allowed be reduced.

    Homosalate and oxybenzone are not being banned, and you don’t need to throw out sunscreens containing these ingredients.

    But if the idea of using them makes you nervous, you can check ingredient lists and buy sunscreens without them.

    What should I look for in a sunscreen?

    When buying a sunscreen there are four non-negotiables. It must have:

    • 30+ or 50+ SPF
    • broad spectrum UV protection (filters both UVB and UVA rays)
    • water-resistant (for staying power in Australia’s sweaty climate)
    • TGA approval mark on the packaging (“AUST L” followed by a number).

    Sunscreen only works if you use it, so choose a sunscreen you like enough to actually wear.

    There are milks, gels and creams, unscented, matte, tinted and many other varieties. Since faces are often the most sensitive, many people use a specialty sunscreen for the face and a cheaper, general one for the rest of the body.

    Spray-on sunscreen is not recommended, however, because it’s too hard to apply enough.

    You need to apply more than you think

    Sunscreen works best when you apply it 20 minutes before you go into the sun, and reapply every two hours and after swimming, sport or towel drying.

    How you apply it affects how well it works. You need about one teaspoon each for:

    • your face and neck
    • back
    • chest and abdomen
    • each arm and leg.

    It’s also common to miss your ears, hands, feet and back of the neck – don’t forget these either.

    Sunscreen usually lasts two to three years stored below 30°C, so keep an eye on the use-by date and follow any instructions about shaking before use.

    If the sunscreen seems to have separated into thinner and thicker layers even after shaking, the ingredients providing SPF may not be mixed evenly throughout and might not work properly.

    But remember – sunscreen isn’t a suit of armour

    If you’re planning to be out in the sun for more than a few minutes at a time, slip on sun-protective clothing and slap on a hat. Use sunscreen to protect the areas you can’t easily cover.

    Slide on sunnies and seek shade where possible to complete your sun-protection practice for a burn-free summer.

    Katie Lee, Postdoctoral Researcher, Dermatology Research Centre, The University of Queensland

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Ultra-Processed People – by Dr. Chris van Tulleken

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It probably won’t come as a great surprise to any of our readers that ultra-processed food is—to make a sweeping generalization—not fabulous for the health. So, what does this book offer beyond that?

    Perhaps this book’s greatest strength is in showing not just what ultra-processed foods are, but why they are. In principle, food being highly processed should be neither good nor bad by default. Much like GMOs, if a food is modified to be more nutritious, that should be good, right?

    Only, that’s mostly not what happens. What happens instead is that food is modified (be it genetically or by ultra-processing) to be cheaper to produce, and thus maximise the profit margin.

    The addition of a compound that increases shelf-life but harms the health, increases sales and is a net positive for the manufacturer, for instance. Dr. van Tulleken offers us many, many, examples and explanations of such cost-cutting strategies at our expense.

    In terms of qualifications, the author has an MD from Oxford, and also a PhD, but the latter is in molecular virology; not so relevant here. Yet, we are not expected to take an “argument from authority”, and instead, Dr. van Tulleken takes great pains to go through a lot of studies with us—the good, the bad, and the misleading.

    If the book has a downside, then this reviewer would say it’s in the format; it’s less a reference book, and more a 384-page polemic. But, that’s a subjective criticism, and for those who like that sort of thing, that is the sort of thing that they like.

    Click here to check out Ultra-Processed People, and understand better what you are putting in your body!

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  • The Dietary Change That Turns Hair Cells & Skin Cells Into Each Other

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    …and other items from this week’s health news:

    Hair today, skin tomorrow?

    Hair follicle stem cells (HFSCs), best known for maintaining hair growth, have shown they can also skin repair when needed, by “switching teams” and becoming skin cells.

    A key trigger for this shift is the availability of serine—a non-essential amino acid found in foods like meats, animal milks, and grains. When serine levels drop, either through diet or metabolic disruption, the stress response kicks in, prompting HFSCs to pause hair production and focus instead on healing damaged skin; this becomes even more pronounced when the skin is injured—which prompts HFSCs to strongly favor wound repair over hair regeneration, accelerating the healing process.

    While reducing serine intake helps strongly push HFSCs toward repair mode, doing the opposite and increasing dietary serine only modestly boosts hair growth, suggesting that the body tightly controls circulating serine levels:

    Read in full: Restricting 1 amino acid in food could speed wound healing

    Related: The Diet That Slows Skin Aging

    Healthy heart, healthy everything else

    At 10almonds we often say “healthy heart; healthy brain“, because the former feeds the latter (with oxygen and nutrients) and plays its part in ultimately taking away detritus (thus avoiding build-ups of harmful proteins that are implicated in Alzheimer’s and Parkinson’s, amongst other dementias).

    However, the same is also true for the rest of the body, making heart health truly critical to every other kind of health—for example, a review of hundreds of studies found that people with heart-healthy lifestyles were more likely to preserve brain and lung function, vision, hearing, muscle strength, and dental health as they aged.

    Beyond that, they also had lower risks of stress, chronic diseases (e.g. cancer, diabetes, COPD, dementia, fatty liver disease), and mental health conditions like depression:

    Read in full: Heart-healthy habits benefit entire body from head to toe, study finds

    Related: Your Health Audit, From Head To Toe

    Good news for late-night snack-artists

    “Don’t eat late at night!”, the common advice goes.

    Researchers (Dr. Chelsea Price et al.), investigated this and found that eating a whole avocado (minus the skin and stone) at night led to slightly lower triglyceride levels before breakfast and significantly lower levels three hours after breakfast, compared to a low-fat snack or a processed snack with similar fat and fiber.

    This is important, because high triglyceride levels are linked to insulin resistance and increased heart disease risk in people with prediabetes; thus, lowering them generally supports metabolic and cardiovascular health, and in this case, helps mitigate diabetic or prediabetic symptoms.

    However, it’s worth noting that:

    1. It was a small (n=27) study
    2. It was funded by the Avocado Nutrition Center

    Now, we don’t know to what extent “Big Avocado” is (or isn’t) contributing to publication bias here, but it’s something to bear in mind.

    Read in full: Nighttime avocado snack may support heart health in prediabetic adults

    Related: The Prediabetes Diet Plan: How to Reverse Prediabetes and Prevent Diabetes Through Healthy Eating and Exercise – by Hillary Wright, M.Ed., RDN

    Take care!

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  • Improve Blood Flow & Circulation In Your Legs

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Dr. Doug Weiss, a physiotherapist (and thus: a doctor of physical therapy), has advice on how and why to increase blood flow and circulation in your legs, keeping yourself healthier for longer and avoiding a lot of potential unpleasantries.

    The exercises

    The exercises here are not complex; they are as follows, and he suggests 3 sets of 10 reps of each, daily:

    • Sitting ankle pumps: sitting on a chair or the edge of a bed, lift the toes up, then heels up, squeezing the muscles.
    • Sitting knee extensions: sitting as before, kick one leg up until knee is straight, then switch legs.
    • Heel raises: standing this time, with a sturdy support such as a countertop, raise on toes as high as possible, then lower heels back to the ground
    • Pillow squats: placing pillows on a chair, cross hands on chest, and simply stand up and sit down—similar to the “getting up off the floor without using your hands” exercise, but an easier version.

    For visuals on these, and more details including the specific benefits of each, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    4 Tips To Stand Without Using Hands ← this time it’s the full movement, from the floor, and this is a really important movement to be able to do, as it’s a big indicator of healthy longevity

    Take care!

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  • Heal & Reenergize Your Brain With Optimized Sleep Cycles

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Sometimes 8 hours sleep can result in grogginess while 6 hours can result in waking up fresh as a daisy, so what gives? Dr. Tracey Marks explains, in this short video.

    Getting more than Zs in

    Sleep involves 90-minute cycles, usually in 4 stages:

    1. Stage 1: (drowsy state): brief muscle jerks; lasts a few minutes.
    2. Stage 2: (light sleep): sleep spindles for memory consolidation; 50% of total sleep.
    3. Stage 3 (deep sleep): tissue repair, immune support, brain toxin removal via the glymphatic system.
    4. Stage 4 (REM sleep): emotional processing, creativity, problem-solving, and dreaming.

    Some things can disrupt some or all of those. To give a few common examples:

    • Alcohol: impairs REM sleep.
    • Caffeine: hinders deep sleep even if consumed hours before bed.
    • Screentime: delays sleep onset due to blue light (but not by much); the greater problem is that it can also disrupt REM sleep due to mental stimulation.

    To optimize things, Dr. Marks recommends:

    • 90-minute rule: plan sleep to align with full cycles (e.g: 22:30 to 06:00 = 7½ hours, which is 5x 90-minute cycles).
    • Smart alarms: use sleep-tracking apps with built-in alarm, to wake you up during light sleep phases.
    • Strategic naps: keep naps to 20 minutes or a full 90-minute cycle.
    • Pink noise: improves deep sleep.
    • Meal timing: avoid eating within 3 hours of bedtime.
    • Natural light: get morning light exposure in the morning to strengthen circadian rhythm.

    For more on all of this, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    Calculate (And Enjoy) The Perfect Night’s Sleep

    Take care!

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  • The Blood Sugar Solution – by Dr. Mark Hyman

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    The main purpose of this book is combating metabolic disease, the amalgam of what’s often prediabetes (sometimes fully-fledged diabetes) and cardiovascular disease (sometimes fully-fledged heart disease).

    To achieve this (after an introductory section explaining what the sociomedical problems are and why the sociomedical problems are happening), he offers a seven-step program; we’ll not keep those steps a mystery; they are:

    1. Boost your nutrition
    2. Regulate your hormones
    3. Reduce inflammation
    4. Improve your digestion
    5. Maximize detoxification
    6. Enhance energy metabolism
    7. Soothe your mind

    Thereafter, it’s all about leading the reader by the hand through the steps; he also offers a six-week action plan, and a six-week meal plan with recipes.

    The style is very sensationalist (too sensationalist for this reviewer’s personal taste) but nevertheless backed up with hard science when it comes to hard claims. So, if you don’t mind wading through (or skipping) some early chapters that are a bit “used car salesman” in feel, there’s actually a lot of good information, especially in the middle of the book, and useful practical guides in the middle and end.

    Bottom line: if you want a good comprehensive science-based practical guide to addressing the risk of metabolic disease, this is that.

    Click here to check out The Blood Sugar Solution, and look after yours!

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