The BAT-pause!

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When Cold Weather & The Menopause Battle It Out

You may know that (moderate, safe) exposure to the cold allows our body to convert our white and yellow fat into the much healthier brown fat—also called brown adipose tissue, or “BAT” to its friends.

If you didn’t already know that, then well, neither did scientists until about 15 years ago:

The Changed Metabolic World with Human Brown Adipose Tissue: Therapeutic Visions

You can read more about it here:

Cool Temperature Alters Human Fat and Metabolism

This is important, especially because the white fat that gets converted is the kind that makes up most visceral fat—the kind most associated with all-cause mortality:

Visceral Belly Fat & How To Lose It ← this is not the same as your subcutaneous fat, the kind that sits directly under your skin and keeps you warm; this is the fat that goes between your organs and of which we should only have a small amount!

The BAT-pause

It’s been known (since before the above discovery) that BAT production slows considerably as we get older. Not too shocking—after all, many metabolic functions slow as we get older, so why should fat regulation be any different?

But! Rodent studies found that this was tied less to age, but to ovarian function: rats who underwent ovariectomies suffered reduced BAT production, regardless of their age.

Naturally, it’s been difficult to recreate such studies in humans, because it’s difficult to find a large sample of young adults willing to have their ovaries whipped out (or even suppressed chemically) to see how badly their metabolism suffers as a result.

Nor can an observational study (for example, of people who incidentally have ovaries removed due to ovarian cancer) usefully be undertaken, because then the cancer itself and any additional cancer treatments would be confounding factors.

Perimenopausal study to the rescue!

A recent (published last month, at time of writing!) study looked at women around the age of menopause, but specifically in cohorts before and after, measuring BAT metabolism.

By dividing the participants into groups based on age and menopausal status, and dividing the post-menopausal group into “takes HRT” and “no HRT” groups, and dividing the pre-menopausal group into “normal ovarian function” and “ovarian production of estrogen suppressed to mimic slightly early menopause” groups (there’s a drug for that), and then having groups exposed to warm and cold temperatures, and measuring BAT metabolism in all cases, they were able to find…

It is about estrogen, not age!

You can read more about the study here:

“Good” fat metabolism changes tied to estrogen loss, not necessarily to aging, shows study

…and the study itself, here:

Brown adipose tissue metabolism in women is dependent on ovarian status

What does this mean for men?

This means nothing directly for (cis) men, sorry.

But to satisfy your likely curiosity: yes, testosterone does at least moderately suppress BAT metabolism—based on rodent studies, anyway, because again it’s difficult to find enough human volunteers willing to have their testicles removed for science (without there being other confounding variables in play, anyway):

Testosterone reduces metabolic brown fat activity in male mice

So, that’s bad per se, but there isn’t much to be done about it, since the rest of your (addressing our male readers here) metabolism runs on testosterone, as do many of your bodily functions, and you would suffer many unwanted effects without it.

However, as men do typically have notably less body fat in general than women (this is regulated by hormones), the effects of changes in BAT metabolism are rather less pronounced in men (per testosterone level changes) than in women (per estrogen level changes), because there’s less overall fat to convert.

In summary…

While menopausal HRT is not necessarily a silver bullet to all metabolic problems, its BAT-maintaining ability is certainly one more thing in its favor.

See also:

Dr. Jen Gunter | What You Should Have Been Told About The Menopause Beforehand

Take care!

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  • Healthy Made Simple – by Ella Mills

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    Often, cookbooks leave a gap between “add the beans to the rice, then microwave” and “delicately embarrass the green-shooted scallions with assiduous garlic before adding to the matelote of orrazata flamed in Sapient Pear Brandy”. This book fills that gap:

    It has dishes good for entertaining, and dishes good for eating on a Tuesday night after a long day. Sometimes, they’re even the same dishes.

    It has a focus on what’s pleasing, easy, healthy, and consistent with being cooked in a real home kitchen for real people.

    The book offers 75 recipes that:

    1. Take under 30 minutes to make*
    2. Contain 10 ingredients or fewer
    3. Have no more than 5 steps
    4. Are healthy and packed with goodness
    5. Are delicious and flavorful

    *With a selection for under 15 minutes, too!

    A strength of the book is that it’s based on practical, real-world cooking, and as such, there are sections such as “Prep-ahead [meals]”, and “cook once, eat twice”, etc.

    Just because one is cooking with simple fresh ingredients doesn’t mean that everything bought today must be used today!

    Bottom line: if you’d like simple, healthy recipe ideas that lend themselves well to home-cooking and prepping ahead / enjoying leftovers the next day, this is an excellent book for you.

    Click here to check out Healthy Made Simple, enjoy the benefits to your health, the easy way!

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  • How Your Exercise Today Gives A Brain Boost Tomorrow

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Regular 10almonds readers may remember we not long back wrote about a study that showed how daily activity levels, in aggregate, make a difference to brain health over the course of 1–2 weeks (in fact, it was a 9-day study):

    Daily Activity Levels & The Measurable Difference They Make To Brain Health

    Today, we’re going to talk about a new (published today, at time of writing) study that shows the associations between daily exercise levels (amongst other things) and how well people performed in cognitive tests the next day.

    By this we mean: they recorded exercise vs sedentary behavior vs sleep on a daily basis (using wearable tech to track it), and tested them daily with cognitive tests, and looked at how the previous day’s activities (or lack thereof) impacted the next day’s test results.

    Notably, the sample was of older adults (aged 50–83). The sample size wasn’t huge but was statistically significant (n=76) and the researchers are of course calling for more studies to be done with more people.

    What they found

    To put their findings into few words:

    • Consistent light exercise boosts general cognitive performance not just for hours (which was already known) but through the next day.
    • More moderate or vigorous activity than usual in particular led to better working memory and episodic memory the next day.
    • More sleep (especially slow-wave deep sleep) improved episodic memory and psychomotor speed.
    • Sedentary behavior was associated with poorer working memory.

    Let’s define some terms:

    • general cognitive performance = average of scores across the different tests
    • working memory = very short term memory, such as remembering what you came into this room for, or (as an example of a test format) being able to take down a multi-digit number in one go without it being broken down (and then, testing with longer lengths of number until failure)
    • episodic memory = memory of events in a narrative context, where and when they happened, etc
    • psychomotor speed = the speed of connection between perception and reaction in quick-response tests

    These are, of course, all useful things to have, which means the general advice here is to:

    • move more, generally
    • exercise more, specifically
    • sit less, whenever reasonably possible
    • sleep well

    You can read the study itself here:

    Associations of accelerometer-measured physical activity, sedentary behaviour, and sleep with next-day cognitive performance in older adults: a micro-longitudinal study

    Want to know the best kind of exercise for brain health?

    Check out our article about neuroscientist Dr. Suzuki, and what she has to say about it:

    The Exercise That Protects Your Brain

    Enjoy!

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  • What Happens To Your Body When You Do Squats Every Day-Not Just For Legs!

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Squat Every Day? Yes, Please!

    It’s back to basics with this video (below). Passion for Health’s video, “What Happens To Your Body When You Do Squats Every Day-Not Just For Legs!” really brings home how squats aren’t just a one-trick pony for your legs.

    The humble bodyweight squat is shown to contribute to everything from bolstering all-around lower body strength to bettering bone density and increasing metabolism.

    Indeed, squats are so powerful that we reviewed a whole book that focuses just on the topic of squatting. Other, broader books on exercise also focus on the positive impacts that squatting can make.

    A proper squat goes beyond your legs, engaging your core, enhancing joint health, and, some argue, can lead to improved balance and circulation.

    (Plus, they’re easy to execute, given they can be done anywhere, without any equipment).

    This is probably why Luigi Fontana and Dr Rangan Chatterjee have spoken about the benefits of squatting.

    How Should We Start?

    The video goes beyond the ‘why’ and delves into the ‘how’, offering step-by-step squatting techniques.

    It answers the burning question: should you really be doing squats every day? 

    (Hint: the answer is most likely “yes”).

    Of course, some of us may not be able to squat, and for those, we’ll feature alternatives in a future article.

    For beginners, the advice is to start slow, aiming for 10 repetitions. You can gradually increase that count as you feel your muscles strengthen. Experienced gym-goers might push for 20 or more reps, adding variations like jump squats for an extra challenge.

    The key takeaway is to listen to your body and ensure rest days for muscle recovery.

    At the end of the day, Passion for Health’s video is a treasure trove for squat lovers, from novices to the seasoned, and insists on the importance of form, frequency, and listening to one’s body.

    How did you find that video? If you’ve discovered any great videos yourself that you’d like to share with fellow 10almonds readers, then please do email them to us!

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  • To Nap Or Not To Nap; That Is The Question

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    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Is it good to nap in the afternoon, or better to get the famous 7 to 9 hours at night and leave it at that? I’m worried that daytime napping to make up for a shorter night’s sleep will just perpetuate and worsen it in the long run, is there a categorical answer here?❞

    Short version: generally considered best is indeed the 7–9 hours at night (yes, including at older ages):

    Why You Probably Need More Sleep

    …and sleep efficiency does matter too:

    Why 7 Hours Sleep Is Not Enough

    …which in turn, is influenced by factors other than just length and depth:

    The 6 Dimensions Of Sleep (And Why They Matter)

    However! Knowing what is best in theory does not help at all if it’s unattainable in practice. So, if you’re not getting a good night’s sleep (and we’ll assume you’re already practising good sleep hygiene; fresh bedding, lights-off by a certain time, no alcohol or caffeine before bed, that kind of thing), then a first port-of-call may be sleep remedies:

    Safe Effective Sleep Aids For Seniors

    If even those don’t work, then napping is now likely your best back-up option. But, napping done incorrectly can indeed cause as many problems as it solves. There’s a difference between:

    • “I napped and now I have energy again” and you continue with your day
    • Darkness took me, and I strayed out of thought and time. Stars wheeled overhead, and every day was as long as the life age of the earth—but it was not the end.” and now you’re not sure whether it’s day or night, whose house you’re in, or whether you’ve been drugged.

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    Take care!

    Don’t Forget…

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    Learn to Age Gracefully

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  • Mango vs Pineapple – Which is Healthier?

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    Our Verdict

    When comparing mango to pineapple, we picked the pineapple.

    Why?

    It was close! Both of these tropical fruits have almost identical macros, and when it comes to vitamins and minerals, mango has slightly more vitamins while pineapple has slightly more minerals, so that balances out too. Their glycemic loads are 11 and 13 respectively, so: very low, and very similar.

    See also: Which Sugars Are Healthier, And Which Are Just The Same?

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    Mango has a lot of vitamin A, to the point that it can interfere with blood-thinners if you take those.

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    Since bromelain is found only in pineapples, whereas vitamin A is easy to find in abundance in many foods, we went with the pineapple.

    Enjoy!

    Don’t Forget…

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  • Spark – by Dr. John Ratey

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We all know that exercise is good for mental health as well as physical. So, what’s so revolutionary about this “revolutionary new science of exercise and the brain”?

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    The book also covers not just “exercise has these benefits”, but also the “how this works” of all kinds of brain benefits, including:

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    In short: this book will tell you what you need to know to get you doing the exercises you need to enjoy those benefits—very much worth it!

    Click here to get “Spark” from Amazon today!

    Don’t Forget…

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    Learn to Age Gracefully

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