The Circadian Rhythm: Far More Than Most People Know
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
The Circadian Rhythm: Far More Than Most People Know
This is Dr. Satchidananda (Satchin) Panda, the scientist behind the discovery of the blue-light sensing cell type in the retina, and the many things it affects. But, he’s discovered more…
First, what you probably know (with a little more science)
Dr. Panda discovered that melanopsin, a photopigment, is “the primary candidate for photoreceptor-mediated entrainment”.
To put that in lay terms, it’s the brain’s go-to for knowing approximately what time of day or night it is, according to how much light there is (or isn’t), and how long it has (or hasn’t) been there.
But… the brain’s “go-to” isn’t the only method. By creating mice without melanopsin, he was able to find that they still keep a circadian rhythm, even in complete darkness:
Melanopsin (Opn4) Requirement for Normal Light-Induced Circadian Phase Shifting
In other words, it was a helpful, but not completely necessary, means of keeping a circadian rhythm.
So… What else is going on?
Dr. Panda and his team did a lot of science that is well beyond the scope of this main feature, but to give you an idea:
- With jargon: it explored the mechanisms and transcription translation negative feedback loops that regulate chronobiological processes, such as a histone lysine demathlyase 1a (JARID1a) that enhances Clock-Bmal1 transcription, and then used assorted genomic techniques to develop a model for how JARID1a works to moderate the level of Per transcription by regulating the transition between its repression and activation, and discovered that this heavily centered on hepatic gluconeogenesis and glucose homeostasis, facilitated by the protein cryptochrome regulating the fasting signal that occurs when glucagon binds to a G-protein coupled receptor, triggering CREB activation.
- Without jargon: a special protein tells our body how to respond to eating/fasting at different times of day—and conversely, certain physiological responses triggered by eating/fasting help us know what time of day it is.
- Simplest: our body keeps on its best cycle if we eat at the same time every day
This is important, because our circadian rhythm matters for a lot more than sleeping/waking! Take hormones, for example:
- Obvious hormones: testosterone and estrogen peak in the mornings around 9am, progesterone peaks between 10pm and 2am
- Forgotten hormones: cortisol peaks in the morning around 8:30am, melatonin peaks between 10pm and 2am
- More hormones: ghrelin (hunger hormone) peaks around 10am, leptin (satiety hormone) peaks 20 minutes after eating a certain amount of satiety-triggering food (protein does this most quickly), insulin is heavily tied to carbohydrate intake, but will still peak and trough according to when the body expects food.
What does this mean for us in practical terms?
For a start, it means that intermittent fasting can help guard against metabolic and related diseases (including inflammation, and thus also cancer, diabetes, arthritis, and more) a lot more if we practice it with our circadian rhythm in mind.
So that “8-hour window” for eating, that many intermittent fasting practitioners adhere to, is going to do much, much better if it’s 10am to 6pm, rather than, say, 4pm to midnight.
Additionally, Dr. Panda and his team found that a 12-hour eating window wasn’t sufficient to help significantly.
Some other take-aways:
- For reasons beyond the scope of this article, it’s good to exercise a) early b) before eating, so getting in some exercise between 8.30am and 10am is ideal
- It also means it’s beneficial to “front-load” eating, so a large breakfast at 10am, and smaller meals/snacks afterwards, is best.
- It also means that getting sunlight (even if cloud-covered) around 8.30am helps guard against metabolic disorders a lot, since the light remains the body’s go-to way of knowing the time.
- We realize that sunlight is not available at 8.30am at all latitudes at all times of year. Artificial is next-best.
- It also means sexual desire will typically peak in men in the mornings (per testosterone) and women in the evenings (per progesterone), but this is just an interesting bit of trivia, and not so relevant to metabolic health
What to do next…
Want to stabilize your own circadian rhythm in the best way, and also help Dr. Panda with his research?
His team’s (free!) app, “My Circadian Clock”, can help you track and organize all of the body’s measurable-by-you circadian events, and, if you give permission, will contribute to what will be the largest-yet human study into the topics covered today, to refine the conclusions and learn more about what works best.
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Recommended
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
How To *Really* Pick Up (And Keep!) Those Habits
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
The Healthiest Habit-Building
Why was that book “Atomic Habits” called that? It wasn’t just because it’s a catchy title…
Habits are—much like atoms—things that are almost imperceptibly small, yet when stacked, they make up the substance of many much larger and more obvious things, and also contain an immense amount of potential power.
About that power…
Habits are the “compound interest” of natural human life. Every action we take, every decision we make, makes our life (often imperceptibly) better or worse. But getting even just 1% better or 1% worse at something every day? That’s going to not just add up over time… It’ll actively compound over time.
Habits will snowball one way or the other, good or bad. So, we want to control that snowball so that it works for us rather than against us.
Thus, we need to choose habits that are helpful to us, rather than those that are harmful to us. Top examples include:
- Making healthy food choices rather than unhealthy ones
- Moving our body regularly rather than being sedentary
- Having a good bedtime/morning routine rather than a daily chaotic blur
- Learning constantly rather than digging into old beliefs out of habit
- Forging healthy relationships rather than isolating ourselves
We all know that to make a habit stick, we need to practice it regularly, with opinions varying on how long it takes for something to become habit. Some say 21 days; some say 66. The number isn’t the important part!
What is important
You will never get to day 66, much less will you get to day 366, if you don’t first get to day 6 (New Year’s Resolutions, anyone?).
So in the early days especially, when the habit is most likely to get dropped, it’s critical to make the habit as easy as possible to form.
That means:
- The habit should be made as pleasant as possible
- (e.g. by making modifications to it if it’s not already intrinsically pleasant)
- The habit should take under 2 minutes to do at first
- (no matter if it takes longer than 2 minutes to be useful; it’ll never be useful if you don’t first get it to stick, so make your initial commitment only 2 minutes, just to get in the habit)
- The habit should have cues to remind you
- (as it’s not habit yet, you will need to either set a reminder on your phone, or leave a visual reminder, such as your workout clothes laid out ready for you in the morning, or a bowl of fruit in plain view where you spend a lot of time)
What gets measured, gets done
Streaks are a great way to do this. Habit-tracking apps help. Marks on a calendar or in a journal are also totally fine.
What can help especially, and that a lot of people don’t do, is to have a system of regular personal reviews—like a work “performance review”, but for oneself and one’s own life.
Set a reminder or write on the calendar / in your diary, to review monthly, or weekly if you prefer, such things as:
- How am I doing in the areas of life that are important to me?
- Have a list of the areas of life that are important to you, by the way, and genuinely reflect on each of them, e.g:
- Health
- Finances
- Relationships
- Learning
- Sleep
- Etc
- Have a list of the areas of life that are important to you, by the way, and genuinely reflect on each of them, e.g:
- What is working for me, and what isn’t working for me?
- What will I do better in this next month/week?
…and then do it!
Good luck, and may it all stack up in your favor!
Share This Post
The Seven-Day Sleep Prescription – by Dr. Aric Prather
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
You probably already know about sleep hygiene. So, what does this book have to offer?
Dr. Aric Prather offers seven days’ worth of adjustments, practices to take up, from when you get up in the morning to when you lay your head down at night.
Some you’ll surely be familiar with, like avoiding blue light and social media at night.
Others, you might not be familiar with, like scheduling 15 minutes for worrying in the daytime. The rationale for this one is that when you find yourself inclined to worry at a time that will keep you awake, you’ll know that you can put off such thoughts to your scheduled “worrying time”. That they’ll be addressed then, and that you can thus sleep soundly meanwhile.
Where the book really comes into its own is in such things as discussing how to not just manage sleep debt, but how to actually use it in your favour.
Nor does Dr. Prather shy away from the truths of our world… That the world these days is not built for us to sleep well. That there are so many other priorities; to get our work done, to succeed and achieve, to pay bills, to support our kids and partners. That so many of these things make plenty of sense in the moment, but catch up with us eventually.
Bottom line: what this book aims to give is a genuinely sustainable approach to sleeping—controlling what we can, and working with what we can’t. If you’d like to have a better relationship with sleep, this book is an excellent choice.
Click here to check out the Seven-Day Sleep Prescription, and improve yours!
Share This Post
The Osteoporosis Breakthrough – by Dr. Doug Lucas
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
“Osteoporosis” and “break” often don’t go well together, but here they do. So, what’s the breakthrough here?
There isn’t one, honestly. But if we overlook the marketing choices and focus on the book itself, the content here is genuinely good:
The book offers a comprehensive multivector approach to combatting osteoporosis, e.g:
- Diet
- Exercise
- Other lifestyle considerations
- Supplements
- Hormones
- Drugs
The author considers drugs a good and important tool for some people with osteoporosis, but not most. The majority of people, he considers, will do better without drugs—by tackling things more holistically.
The advice here is sound and covers all reasonable angles without getting hung up on the idea of there being a single magical solution for all.
Bottom line: if you’re looking for a book that’s a one-stop-shop for strategies against osteoporosis, this is a good option.
Click here to check out The Osteoporosis Breakthrough, and keep your bones strong!
Share This Post
Related Posts
Getting Flexible, Starting As An Adult: How Long Does It Really Take?
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Aleks Brzezinska didn’t start stretching until she was 21, and here’s what she found:
We’ll not stretch the truth
A lot of stretching programs will claim “do the splits in 30 days” or similar, and while this may occasionally be true, usually it’ll take longer.
Brzezinska started stretching seriously when she was 21, and made significant flexibility gains between the ages of 21 and 23 with consistent practice. Since then, she’s just maintained her flexibility.
There are facts that affect progress significantly, such as:
- Anatomy: body structure, age, and joint flexibility do influence flexibility; starting younger and/or having hypermobile joints does make it easier.
- Consistency: regular practice (2–3 times a week) is crucial, but avoid overdoing it, especially when sore.
- Lifestyle: weightlifting, running, and similar activities can tighten muscles, making flexibility harder to achieve.
- Hydration: staying hydrated is important for muscle flexibility.
She also recommends incorporating a variety of different stretching types, rather than just one method, for example passive stretching, active stretching, Proprioceptive Neuromuscular Facilitation (PNF) stretching, and mobility work.
For more on each of these, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like:
Jasmine McDonald’s Ballet Stretching Routine
Take care!
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
Mineral-Rich Mung Bean Pancakes
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Mung beans are rich in an assortment of minerals, especially iron, copper, phosphorus, and magnesium. They’re also full of protein and fiber! What better way to make pancakes healthy?
You will need
- ½ cup dried green mung beans
- ½ cup chopped fresh parsley
- ½ cup chopped fresh dill
- ¼ cup uncooked wholegrain rice
- ¼ cup nutritional yeast
- 1 tsp MSG, or 2 tsp low-sodium salt
- 2 green onions, finely sliced
- 1 tbsp extra virgin olive oil
Method
(we suggest you read everything at least once before doing anything)
1) Soak the mung beans and rice together overnight.
2) Drain and rinse, and blend them in a blender with ¼ cup of water, to the consistency of regular pancake batter, adding more water (sparingly) if necessary.
3) Transfer to a bowl and add the rest of the ingredients except for the olive oil, which latter you can now heat in a skillet over a medium-high heat.
4) Add a few spoonfuls of batter to the pan, depending on how big you want the pancakes to be. Cook on both sides until you get a golden-brown crust, and repeat for the rest of the pancakes.
5) Serve! As these are savory pancakes, you might consider serving them with a little salad—tomatoes, olives, and cucumbers go especially well.
Enjoy!
Want to learn more?
For those interested in some of the science of what we have going on today:
- Why You’re Probably Not Getting Enough Fiber (And How To Fix It)
- What’s The Deal With MSG?
- All About Olive Oils: Is “Extra Virgin” Worth It?
Take care!
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
Insomnia? High blood pressure? Try these!
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Your Questions, Our Answers!
Q: Recipes for insomnia and high blood pressure and good foods to eat for these conditions?
A: Insomnia can be caused by many things, and consequently can often require a very multi-vector approach to fixing it. But, we’ll start by answering the question you asked (and probably address the rest of dealing with insomnia in another day’s edition!):
- First, you want food that’s easy to digest. Broadly speaking, this means plant-based. If not plant-based, fish (unless you have an allergy, obviously) is generally good and certainly better than white meat, which is better than red meat. In the category of dairy, it depends so much on what it is, that we’re not going to try to break it down here. If in doubt, skip it.
- You also don’t want blood sugar spikes, so it’s good to lay off the added sugar and white flour (or white flour derivatives, like white pasta), especially in your last meal of the day.
- Magnesium supports healthy sleep. A fine option would be our shchi recipe, but using collard greens rather than cabbage. Cabbage is a wonderful food, but collard greens are much higher in magnesium. Remember to add plenty of mushrooms (unless you don’t like them), as they’re typically high in magnesium too.
As for blood pressure, last month we gave tips (and a book recommendation) for heart health. The book, Dr. Monique Tello’s “Healthy Habits for Your Heart: 100 Simple, Effective Ways to Lower Your Blood Pressure and Maintain Your Heart’s Health”, also has recipes!
Here’s one from the “mains” section:
Secret Ingredient Baltimore-Style Salmon Patties with Not-Oily Aioli
❝This is a family favorite, and no one knows that it features puréed pumpkin! Most salmon cake recipes all for eggs and bread crumbs as binders, but puréed pumpkin and grated carrot work just as well, lend a beautiful color, and add plenty of fiber and plant nutrients. Canned salmon is way cheaper than fresh and has just as much omega-3 PUFAs and calcium. Serve this alongside a salad (the Summer Corn, Tomato, Spinach, and Basil Salad would go perfectly) for a well-rounded meal.❞
Serves 4 (1 large patty each)
Secret Ingredient Baltimore-Style Salmon Patties:
- 1 (15-oz) can pink salmon, no salt added
- ½ cup puréed pumpkin
- ½ cup grated carrot (I use a handheld box grater)
- 2 tablespoons minced chives (Don’t have chives? Minced green onions or any onions will do)
- 2 teaspoons Old Bay Seasoning
- 1 tablespoon olive oil
- ½ large lemon, sliced, for serving
Not-Oily Aioli:
- ½ cup plain low-fat Greek yogurt
- Juice and zest from ½ large lemon
- 1 clove garlic, crushed and minced fine
- 2 tablespoons chopped fresh dill
- For the patties: mix all the ingredients for the salmon patties together in a medium bowl
- Form patties with your hands and set on a plate or tray (you should have 4 burger-sized patties)
- Heat oil in a large skillet over medium heat.
- Set patties in a skillet and brown for 4 minutes, then carefully flip.
- Brown the other side, then serve hot.
- For the Aioli: mix all the ingredients for the aioli together in a small bowl.
- Plop a dollop alongside or on top of each salmon patty and serve with a spice of lemon.
Per serving: Calories: 367 | Fat: 13.6g | Saturated Fat: 4.4g | Protein: 46g | Sodium: 519mg | Carbohydrates: 13.2g | Fiber: 1.3g | Sugars: 9g | Calcium: 505mg | Iron: 1mg | Potassium 696mg
Notes from the 10almond team:
- If you want to make it plant-based, substitute cooked red lentils (no salt added) for the tinned salmon, and plant-based yogurt for the Greek yogurt
- We recommend adding more garlic. Seriously, who uses 1 clove of garlic for anything, let alone divided between four portions?
- The salads mentioned are given as recipes elsewhere in the same book. We strongly recommend getting her book, if you’re interested in heart health!
Do you have a question you’d like to see answered here? Hit reply or use the feedback widget at the bottom; we’d love to hear from you!
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
