The Fascinating Truth About Aspartame, Cancer, & Neurotoxicity

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Is Aspartame’s Reputation Well-Deserved?

A bar chart showing the number of people who are interested in social media and Aspartame.

In Tuesday’s newsletter, we asked you for your health-related opinions on aspartame, and got the above-depicted, below-described, set of responses:

  • About 47% said “It is an evil carcinogenic neurotoxin”
  • 20% said “It is safe-ish, but has health risks that are worse than sugar”
  • About 19% said “It is not healthy, but better than sugar”
  • About 15% said “It’s a perfectly healthy replacement for sugar”

But what does the science say?

Aspartame is carcinogenic: True or False?

False, assuming consuming it in moderation. In excess, almost anything can cause cancer (oxygen is a fine example). But for all meaningful purposes, aspartame does not appear to be carcinogenic. For example,

❝The results of these studies showed no evidence that these sweeteners cause cancer or other harms in people.❞

~ NIH | National Cancer Institute

Source: Artificial Sweeteners and Cancer

Plenty of studies and reviews have also confirmed this; here are some examples:

Why then do so many people believe it causes cancer, despite all the evidence against it?

Well, there was a small study involving giving megadoses to rats, which did increase their cancer risk. So of course, the popular press took that and ran with it.

But those results have not been achieved outside of rats, and human studies great and small have all been overwhelmingly conclusive that moderate consumption of aspartame has no effect on cancer risk.

Aspartame is a neurotoxin: True or False?

False, again assuming moderate consumption. If you’re a rat being injected with a megadose, your experience may vary. But a human enjoying a diet soda, the aspartame isn’t the part that’s doing you harm, so far as we know.

For example, the European Food Safety Agency’s scientific review panel concluded:

❝there is still no substantive evidence that aspartame can induce such effects❞

~ Dr. Atkin et al (it was a pan-European team of 21 experts in the field)

Source: Report on the Meeting on Aspartame with National Experts

See also,

❝The data from the extensive investigations into the possibility of neurotoxic effects of aspartame, in general, do not support the hypothesis that aspartame in the human diet will affect nervous system function, learning or behavior.

The weight of existing evidence is that aspartame is safe at current levels of consumption as a nonnutritive sweetener.❞

~ Dr. Magnuson et al.

Source: Aspartame: A Safety Evaluation Based on Current Use Levels, Regulations, and Toxicological and Epidemiological Studies

and

❝The safety testing of aspartame has gone well beyond that required to evaluate the safety of a food additive.

When all the research on aspartame, including evaluations in both the premarketing and postmarketing periods, is examined as a whole, it is clear that aspartame is safe, and there are no unresolved questions regarding its safety under conditions of intended use.❞

~ Dr. Stegink et al.

Source: Regulatory Toxicology & Pharmacology | Aspartame: Review of Safety

Why then do many people believe it is a neurotoxin? This one can be traced back to a chain letter hoax from about 26 years ago; you can read it here, but please be aware it is an entirely debunked hoax:

Urban Legends | Aspartame Hoax

Take care!

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    Our Verdict

    When comparing rice to buckwheat, we picked the buckwheat.

    Why?

    It’s a simple one today:

    • The vitamin and mineral profiles are very similar, so neither of these are a swaying factor
    • In terms of macros, rice is higher in carbohydrates while buckwheat is higher in fiber
    • Buckwheat also has more protein, but not by much
    • Buckwheat has the lower glycemic index, and a lower insulin index, too

    While buckwheat cannot always be reasonably used as a substitute for rice (often because the texture would not work the same), in many cases it can be.

    And if you love rice, well, so do we, but variety is also the spice of life indeed, not to mention important for good health. You know that whole “eat 30 different plants per week” thing? Grains count in that tally! So substituting buckwheat in place of rice sometimes seems like a very good bet.

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  • Corn Chips vs Potato Chips: Which is Healthier?

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    Our Verdict

    When comparing corn chips to potato chips, we picked the corn chips.

    Why?

    First, let it be said, this was definitely a case of “lesser evil voting” as there was no healthy choice here. But as for which is relatively least unhealthy…

    Most of the macronutrient and micronutrient profile is quite similar. Both foods are high carb, moderately high fat, negligible protein, and contain some trace minerals and even some tiny amounts of vitamins. Both are unhealthily salty.

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    Corn Chips | Potato Chips

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    Harness The Power Of Your Perfectionism

    A lot of people see perfectionism as a problem—and it can be that!

    We can use perfectionism as a would-be shield against our fear of failure, by putting things off until we’re better prepared (repeat forever, or at least until the deadliniest deadline that ever deadlined), or do things but really struggle to draw a line under them and check them off as “done” because we keep tweaking and improving and improving… With diminishing returns (forever). So, that’s not helpful.

    But, if we’re mindful, we can also leverage our perfectionism to our benefit.

    Great! How?

    First we need to be able to discern the ways in which perfectionism can be bad or good for us. Or as it’s called in psychology, ways in which our perfectionism can be maladaptive or adaptive.

    • Maladaptive: describing a behavioral adaptation to our environment—specifically, a reactive behavioral adaptation that is unhealthy and really is not a solution to the problem at hand
    • Adaptive: describing a behavioral adaptation to our environment—specifically, a responsive behavioral adaptation that is healthy and helps us to thrive

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    • Maladaptive: never taking up that new hobby, because you’re just going to suck at it anyway, and what’s the point if you’re not going to excel? You’re a perfectionist, and you don’t settle for anything less than excellence.
    • Adaptive: researching the new hobby, learning the basics, and recognizing that even if the results are not immediately perfect, the learning process can be… Yes, even with mistakes along the way, for they too are part of learning! You’re a perfectionist, and you’re going to be the best possible student of your new hobby.

    Did you catch the key there?

    When it comes to approaching things we do in life—either because we want to or because we must—there are two kinds of mindset: goal-oriented, and task-oriented.

    Broadly speaking, each has their merits, and as a general topic, it’s beyond the scope of today’s main feature. Here we’re looking at it in the context of perfectionism, and in that frame, there’s a clear qualitative difference:

    • The goal-oriented perfectionist will be frustrated to the point of torment, at not immediately attaining the goal. Everything short of that will be a means to an end, at best. Not fun.
    • The task-oriented perfectionist will take joy in going about the task in the best way possible, and optimizing their process as they go. The journey itself will be rewarding and a tangible product of their consistent perfectionism.

    The good news is: you get to choose! You’re not stuck in a box.

    If you’re thinking “I’m a perfectionist and I’m generally a goal-oriented person”, that’s fine. You’re just going to need to reframe your goals.

    • Instead of: my goal is to be fluent in Arabic
      • …so you never speak it, because to err is human, all too human, and you’re a perfectionist, so you don’t want that!
    • Let’s try: my goal is to study Arabic for at least 15 minutes per day, every day, without fail, covering at least some new material each time, no matter how small the increase
      • …and then you go and throw yourself into conversation way out of your depth, make mistakes, and get corrections, because that’s how you learn, and you’re a perfectionist, so you want that!

    This goes for any field of expertise, of course.

    • If you want to play the violin solo in Carnegie Hall, you have to pick up your violin and practice each day.
    • If you want to be a world-renowned pastry chef, you have to make a consistent habit of baking.
    • If you want to write a bestselling book, you have to show up at your keyboard.

    Be perfect all you want, but be the perfect student.

    And as your skills grow, maybe you’ll upgrade that to also being the perfect practitioner, and perhaps later still, the perfect teacher.

    But just remember:

    Perfection comes not from the end goal (that would be backwards thinking!) but from the process (which includes mistakes; they’re an important part of learning; embrace them and grow!), so perfect that first.

    Don’t Forget…

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