How Do DNA Repair Enzymes Actually Help?

Dr. Andrea Suarez explains:

Are They Worth It?

DNA repair enzymes are what they sound like: enzymes that repair damage to DNA.

They’re derived from bacteria and plants and can function in human cells to fix UV- and oxidation-induced DNA damage.

How they get where they need to be: the enzymes are encapsulated in liposomes, which mimic cell membranes and allow penetration through the stratum corneum. Once inside keratinocytes, the liposomes dissolve and release the enzymes that then reach the nucleus to repair the DNA.

Does it work? The evidence is strong for some claims, not so much for others:

• Sunscreen plus DNA repair enzymes reduced markers of DNA damage and precancerous actinic keratoses more than sunscreen alone.
• Evidence for reducing wrinkles, reducing hyperpigmentation, or improving elasticity is limited and not yet convincing.

Is it safe? Human and animal studies—including in people with xeroderma pigmentosum—show excellent safety, even with long-term use. Rare issues include mild irritation or burning if you get it in your eyes, so maybe don’t put it there.

In few words: while it’s not yet a scientifically sound choice for beauty considerations, it does augment the protective power of sunscreen, on a cellular level, reducing sun-induced DNA damage that not only ages your skin, but also could turn cancerous if left unchecked.

For more on all of this, enjoy:

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Want to try some?

We don’t sell it, but here for your convenience is an example product on Amazon 😎

Be warned, it is pricier than it looks!